Protein Alignment CG12147 and TTBK1

DIOPT Version :9

• Sequence 1: NP_649536.1
• Gene: CG12147 / 40651
• FlyBaseID: FBgn0037325
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: XP_016866853.1
• Gene: TTBK1 / 84630
• HGNCID: 19140
• Length: 1409
• Species: Homo sapiens
• Alignment Length: 439
• Identity: 136/439 - (30%)
• Similarity: 198/439 - (45%)
• Gaps: 99/439 - (22%)

  Fly    44 KDQRQDRRFSEEKQSLP-EIIVAGKYRLLKRIGNGSFGELFQAEGLKYHEKVAIKLESSTVKHPL 107
            ||:.......|:...|| ..:|..::::||:||.|.|||:::|..|...|.||:|:||:.....:
Human     9 KDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQV 73

  Fly   108 LPREARIYGILQGGLGIPHVKHYATEG---AYNVMVMDLLGPTLEDLLNLCSR-SFSMKTTLMLA 168
            |..|..:...|||.   .||..:...|   .:|.:||.|.|..|.||.....| :|::.|||.|.
Human    74 LKMEVAVLKKLQGK---DHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLG 135

  Fly   169 DQILARVELLHRRCFIHRDIKPDNFLMG-LNRHQTQVYMIDFGLAKKFYS----LRTQKHI-GYT 227
            .|||..:|.:|...|:||||||.||.|| |.....:.||:|||||:::.:    :|..::: |:.
Human   136 KQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFR 200

  Fly   228 ENRDLVGTARYASVRAH-YAEQSRRDDLESVGYLLLYFQRGRLPWQGIRAQSQA----QKYEKIA 287
                  ||.|||||.|| ..|..|.|||.|:.|:|:.|..|:|||:.|:.:.|.    :|||.
Human   201 ------GTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEH-- 257

  Fly   288 EYKANIPLQQLCSGLPVEFFMYLKYCRKLHFAEKPDYVYLQQLFKVLFRNQYK----VCDFLFDW 348
                    :.|...:|.||.::|.:...|.:..||||    ||...:|.|..|    ..:..|||
Human   258 --------RMLLKHMPSEFHLFLDHIASLDYFTKPDY----QLIMSVFENSMKERGIAENEAFDW 310

  Fly   349 ------VVLKRES---PEQQSQQKGRERDRGGKRNVVVQKERHRNKDRDSDTQRCRIKNGGDLLE 404
                  .:|...:   |:|.::|...   ..|..||....                    ||||
Human   311 EKAGTDALLSTSTSTPPQQNTRQTAA---MFGVVNVTPVP--------------------GDLL- 351

  Fly   405 IEENESTTGEDPNEDKPQKKHGKACSCSYHLQKKRLQDRDRRAPLMTER 453
             .||        .||..|.:|              |.|::...|::..|
Human   352 -REN--------TEDVLQGEH--------------LSDQENAPPILPGR 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	102/278 (37%)
		SPS1	67..>306	CDD:223589	93/253 (37%)
TTBK1	XP_016866853.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810