DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12147 and ball

DIOPT Version :9

Sequence 1:	NP_649536.1	Gene:	CG12147 / 40651	FlyBaseID:	FBgn0037325	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_651508.1	Gene:	ball / 43228	FlyBaseID:	FBgn0027889	Length:	599	Species:	Drosophila melanogaster

Alignment Length:	490	Identity:	112/490 - (22%)
Similarity:	192/490 - (39%)	Gaps:	89/490 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PQIRKERRHPPQPNHPHEKDQRQDRRFSEEKQSLPEII---------VAGKYRLLKRIGNGSFGE 81
            |::.|.:...|      .|.....::...:...:||.:         ..|::|:...||.|.|||
  Fly     2 PRVAKPKAAAP------AKKVVSAKKAKSKLYKMPEKVKEGTVFTDLAKGQWRIGPSIGVGGFGE 60

  Fly    82 LFQA--EGLKYHEKVAIKLESS-----TVKHPLLPREARIYGILQ-------GGLGIPHVKHYAT 132
            ::.|  .|.|.::.| :|.|..     .|:.....|.|::..|.|       ..||:|::   ..
  Fly    61 IYAACKVGEKNYDAV-VKCEPHGNGPLFVEMHFYLRNAKLEDIKQFMQKHGLKSLGMPYI---LA 121

  Fly   133 EGAYNV-------MVMDLLGPTLEDLLNLCSRSFSMKTTLMLADQILARVELLHRRCFIHRDIKP 190
            .|:..|       :||...|..|...|....:.....|...||.|:|...:.:|...::|.|:|.
  Fly   122 NGSVEVNGEKHRFIVMPRYGSDLTKFLEQNGKRLPEGTVYRLAIQMLDVYQYMHSNGYVHADLKA 186

  Fly   191 DNFLMGLNR-HQTQVYMIDFGLAKKFYSLRTQKHIGYTENRDLVGTARYASVRAHYAEQSRRDDL 254
            .|.|:||.: ...|.|::|||||..|.:...:.......|    ||..|.|..||....:||.||
  Fly   187 ANILLGLEKGGAAQAYLVDFGLASHFVTGDFKPDPKKMHN----GTIEYTSRDAHLGVPTRRADL 247

  Fly   255 ESVGYLLLYFQRGRLPWQGIRAQSQAQKYEKIAE-YKANI--PLQQLC-SGLPVEFFMYLKYCRK 315
            |.:||.|:.:....|||...:..:...|.:|..| :..||  .|:.|. .|:|.....::||..|
  Fly   248 EILGYNLIEWLGAELPWVTQKLLAVPPKVQKAKEAFMDNIGESLKTLFPKGVPPPIGDFMKYVSK 312

  Fly   316 LHFAEKPDYVYLQQLFKVLFRNQYKV-----CDFLFDWVVLKRESPEQQSQQKGRERDRGGKRNV 375
            |...::|||...:..|....: |.|:     .||          ..:.|:.........|..:..
  Fly   313 LTHNQEPDYDKCRSWFSSALK-QLKIPNNGDLDF----------KMKPQTSSNNNLSPPGTSKAA 366

  Fly   376 VVQKERHRNKDRDSDTQRCRIKNGGDLLEIEENESTTGEDPNEDKPQKKHGKACSCSYHLQKKRL 440
            ..:|.:               |....:|....:|..:..:.:|::.:|.|.|..:       |::
  Fly   367 TARKAK---------------KIDSPVLNSSLDEKISASEDDEEEEEKSHRKKTA-------KKV 409

  Fly   441 QDRDRRAPLMTERRIL--SGEQEQELELELRGSPQ 473
            ....|.|.:...:|:.  |...::.::.|.:.:|:
  Fly   410 TPSARNAKVSPLKRVADSSPPSQKRVKTEPKSTPR 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	83/289 (29%)
CG12147	NP_649536.1	SPS1	67..>306	CDD:223589	76/264 (29%)
ball	NP_651508.1	STKc_VRK	36..328	CDD:270917	84/299 (28%)
		SPS1	47..432	CDD:223589	103/425 (24%)
		Pol_alpha_B_N	<399..>502	CDD:285602	10/53 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452728
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11909
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.930