Protein Alignment CG12147 and Ttbk2

DIOPT Version :10

• Sequence 1: NP_649536.1
• Gene: CG12147 / 40651
• FlyBaseID: FBgn0037325
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: XP_006234899.2
• Gene: Ttbk2 / 311349
• RGDID: 1311661
• Length: 1311
• Species: Rattus norvegicus
• Alignment Length: 542
• Identity: 150/542 - (27%)
• Similarity: 227/542 - (41%)
• Gaps: 132/542 - (24%)

  Fly    10 KDDRRWQGRSDVHQSKPQIRKERRHPPQPNHPHEKD------QRQDRRFSEEKQSLPEIIVAG-- 66
            |:...|            :|:|..:....|||.|.|      ..|....|...:. |:|:..|
  Rat    34 KETHSW------------LRREVGNRLNGNHPWELDACVAVLPHQCFAMSGGGEQ-PDILSVGIL 85

  Fly    67 ---KYRLLKRIGNGSFGELFQAEGLKYHEKVAIKLESSTVKHPLLPREARIYGILQGGLGIPHVK 128
               ::::|::||.|.|||::.|..:...|.||:|:||:.....:|..|..:...|||.   .||.
  Rat    86 VKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGK---DHVC 147

  Fly   129 HYATEG---AYNVMVMDLLGPTLEDLLNLCSR-SFSMKTTLMLADQILARVELLHRRCFIHRDIK 189
            .:...|   .:|.:||.|.|..|.||....|| :|::.|||.|..|||..:|.:|...|:|||||
  Rat   148 RFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIK 212

  Fly   190 PDNFLMGLNRHQT---QVYMIDFGLAKKFYS----LRTQKHI-GYTENRDLVGTARYASVRAH-Y 245
            |.||.||  |..:   :.:|:|||||::|.:    :|..:.: |:.      ||.||||:.|| .
  Rat   213 PSNFAMG--RFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFR------GTVRYASINAHRN 269

  Fly   246 AEQSRRDDLESVGYLLLYFQRGRLPWQGIRAQSQAQKYEKIAEYKANIPLQQLCSGLPVEFFMYL 310
            .|..|.|||.|:.|:|:.|..|:|||:.|:.:      |::...|.....:.:...||.||..:|
  Rat   270 REMGRHDDLWSLFYMLVEFVVGQLPWRKIKDK------EQVGSIKERYDHRLMLKHLPPEFSTFL 328

  Fly   311 KYCRKLHFAEKPDYVYLQQLFKVLFRNQYKVCDFL----FDWV---------------------- 349
            .:...|.:..||||    ||...:|.|..|....:    |||.
  Rat   329 DHISSLDYFTKPDY----QLLTSVFDNSIKTFGVIESDPFDWEKSGTDGSLTTTTTSATPQLHTR 389

  Fly   350 -----------------VLKRESPEQQSQQKGRERDRGGKRNVVVQK-------ERHRNKD--RD 388
                             :|:..:.|....::..:.:.|....|...|       .|.:.||  .:
  Rat   390 LTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIPAGVSPDKLPGSLGHPRPQEKDVWEE 454

  Fly   389 SDTQRCRIKNGGDLLEIEENESTTGEDPNEDKPQKKHGK------ACSCSYHLQ-KKRLQDRDRR 446
            .|..:.:||.|......||..|              ||:      |.|....:: :..:...||.
  Rat   455 MDINKNKIKLGICKAATEEENS--------------HGQVNGILNAPSLGSPIRVRSEITQPDRD 505

  Fly   447 APLMTE-RRILSGEQEQELELE 467
            .||:.: |.|.|.|.|:.|.||
  Rat   506 VPLVRKLRSIHSFELEKRLTLE 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	98/276 (36%)
Ttbk2	XP_006234899.2	STKc_TTBK2	89..350	CDD:271031	99/281 (35%)