DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12147 and csnk1a1

DIOPT Version :9

Sequence 1:	NP_649536.1	Gene:	CG12147 / 40651	FlyBaseID:	FBgn0037325	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	XP_009289361.1	Gene:	csnk1a1 / 192307	ZFINID:	ZDB-GENE-020419-19	Length:	365	Species:	Danio rerio

Alignment Length:	351	Identity:	178/351 - (50%)
Similarity:	241/351 - (68%)	Gaps:	39/351 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 SLPEIIVAGKYRLLKRIGNGSFGELFQAEGLKYHEKVAIKLESSTVKHPLLPREARIYGILQGGL 122
            |..|.||.|||:|:::||:||||:::.|..:...|:||:||||...:||.|..|:::|.|||||:
Zfish     7 SKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGV 71

  Fly   123 GIPHVKHYATEGAYNVMVMDLLGPTLEDLLNLCSRSFSMKTTLMLADQILARVELLHRRCFIHRD 187
            ||||::.|..|..|||:|||||||:||||.|.|||.|:|||.||||||:::|:|.:|.:.|||||
Zfish    72 GIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRD 136

  Fly   188 IKPDNFLMGLNRH----------------------------QTQVYMIDFGLAKKFYSLRTQKHI 224
            |||||||||:.||                            ..|:::||||||||:...||::||
Zfish   137 IKPDNFLMGIGRHCNKCLESPVGKRKRSLAVSSSQDPSFSGLNQLFLIDFGLAKKYRDNRTRQHI 201

  Fly   225 GYTENRDLVGTARYASVRAHYA-EQSRRDDLESVGYLLLYFQRGRLPWQGIRAQSQAQKYEKIAE 288
            .|.|:::|.|||||||:.||.. |||||||:||:||:|:||.|..|||||::|.::.||||||:|
Zfish   202 PYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISE 266

  Fly   289 YKANIPLQQLCSGLPVEFFMYLKYCRKLHFAEKPDYVYLQQLFKVLFRNQYKVCDFLFDWVVLKR 353
            .|.:.|::.||.|.|.||.|||.|||.|.|.|.|||:||:|||::|||......|:.|||.:||:
Zfish   267 KKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQ 331

  Fly   354 ESPEQ------QSQQ----KGRERDR 369
            ::.:|      |.||    .|::.|:
Zfish   332 KAAQQAASSGGQGQQAQTPTGKQTDK 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	156/292 (53%)
CG12147	NP_649536.1	SPS1	67..>306	CDD:223589	139/267 (52%)
csnk1a1	XP_009289361.1	STKc_CK1_alpha	16..309	CDD:271030	156/292 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595501
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54222
OrthoDB	1	1.010	-	-		D1097975at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11909
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.820