DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12147 and tag-191

DIOPT Version :9

Sequence 1:	NP_649536.1	Gene:	CG12147 / 40651	FlyBaseID:	FBgn0037325	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_506600.1	Gene:	tag-191 / 179960	WormBaseID:	WBGene00007049	Length:	346	Species:	Caenorhabditis elegans

Alignment Length:	308	Identity:	92/308 - (29%)
Similarity:	147/308 - (47%)	Gaps:	29/308 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 IIVAGKYRLLKRIGNGSFGELFQAEGLKYHEK-VAIKLE--SSTVKHPLLPREARIYGILQGGLG 123
            ::|..|||:::::|.|..|.:::.|.::...| .|:|:|  |:.....:|..|.:|...|   :.
Worm    14 VVVGKKYRVIQQLGQGGCGSVYKVEDIEDKTKQYAMKVEFNSNANAGNVLKMEVQILTHL---VS 75

  Fly   124 IPHVKHYATEG---AYNVMVMDLLGPTLEDLLNLCSRSFSMKTTLMLADQILARVELLHRRCFIH 185
            ..||......|   .|:.:||.|||.:||.|:......|::.|.:.:...:|..::.:|...|||
Worm    76 KNHVAKCMASGKKDRYSYVVMTLLGESLESLMKKHGPFFNVSTQMRIGICLLFGIKQIHDIGFIH 140

  Fly   186 RDIKPDNFLMGLNRHQTQVYMI--DFGLAKKFYSLRTQKHIGYTENRD-----LVGTARYASVRA 243
            ||:||.|..:|......:.|.|  |||||:::.   |.|..|....|.     ..||:||.||..
Worm   141 RDLKPANVALGNKGSPDERYFIVLDFGLARQYI---TDKEDGKKMRRPREKALFRGTSRYCSVAM 202

  Fly   244 H-YAEQSRRDDLESVGYLLLYFQRGRLPWQGIRAQSQAQKYEKIAEYKANIPLQQLCSGLPVEFF 307
            | ..||.|.|||.::.|:|... |.:|.|      |......:|.|.|.::..|.|.:..|::..
Worm   203 HDRFEQGRVDDLWALIYMLAEL-RCQLAW------SDLDDKVEIGEMKRHVADQNLFAKSPIQML 260

  Fly   308 MYLKYCRKLHFAEKPDYVYLQQLFKVLFRN-QYKVCDFLFDWVVLKRE 354
            .::|..|...|..:|||..|..|.....:: :||..| .:.|...||:
Worm   261 EFVKIVRATQFYHRPDYEKLFNLLNDAMKSAKYKWSD-PYHWEPEKRK 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	84/277 (30%)
CG12147	NP_649536.1	SPS1	67..>306	CDD:223589	77/252 (31%)
tag-191	NP_506600.1	STKc_TTBK	19..285	CDD:270919	85/278 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810