Protein Alignment CG12147 and C50F4.10

DIOPT Version :10

• Sequence 1: NP_649536.1
• Gene: CG12147 / 40651
• FlyBaseID: FBgn0037325
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_505456.2
• Gene: C50F4.10 / 179334
• WormBaseID: WBGene00008235
• Length: 317
• Species: Caenorhabditis elegans
• Alignment Length: 302
• Identity: 77/302 - (25%)
• Similarity: 149/302 - (49%)
• Gaps: 33/302 - (10%)

  Fly    67 KYRLLKRIGNGSFGELFQAEG---LKYHEKVAIKLESSTVKHPLLPREARIYGIL--QGGLGIPH 126
            |:.:.|:|..|.|..::...|   :..:::.|:|.||:.....:|..||.:...:  :|......
 Worm    18 KWTIEKKIAQGDFNFIYMCNGSSNMSNYKQFALKCESAQSPLQMLKVEAFVLQTIAKRGSRHFCD 82

  Fly   127 VKHYATEGAYNVMVMDLLGPTLEDLLNL-CSRSFSMKTTLMLADQILARVELLHRRCFIHRDIKP 190
            ::........:.:||.::|..|.|.:.. .|.:.|:...|.:..|::..:|.||...|||||:||
 Worm    83 IEDIGKFQGIHYIVMHMIGRALVDYMKTSMSGAISVNCALSVGIQLIEALEDLHNCGFIHRDLKP 147

  Fly   191 DNFLMG-LNRHQT-QVYMIDFGLAKKFYSLRTQKHIGYTENRDLV---GTARYASVRAHYAEQ-S 249
            .|...| .:|::. ::|::.||:::::...:.|..    :.||.|   ||.||||:..|..:: :
 Worm   148 SNICFGRKDRNELGKLYLLSFGISRRYLDSKNQMR----KPRDNVEFRGTVRYASLNCHQLQELN 208

  Fly   250 RRDDLESVGYLLLYFQRGRLPWQGI-------RAQSQAQKYEKIAEY-KANIPLQQLCSGLPVEF 306
            |:|||||..|:::....|:|||:|:       |.:.|::....||.: :|..|:::|     .|.
 Worm   209 RKDDLESAFYVIVEMITGQLPWKGLPDGAAVARVKQQSRHPSAIALFLRAPCPMEEL-----REV 268

  Fly   307 FMYLKYCRKLHFAEKPDYVYLQQLFKVLFRNQYKVCDFLFDW 348
            .:.:.   ..::...||||.:..:.:...|...:. :..:||
 Worm   269 MILID---SYNYFTAPDYVNICNILRRAMRRSPQP-EHPYDW 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	74/283 (26%)
C50F4.10	NP_505456.2	Protein Kinases, catalytic domain	18..291	CDD:473864	74/284 (26%)