Protein Alignment CG12147 and CSNK1E

DIOPT Version :9

• Sequence 1: NP_649536.1
• Gene: CG12147 / 40651
• FlyBaseID: FBgn0037325
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001885.1
• Gene: CSNK1E / 1454
• HGNCID: 2453
• Length: 416
• Species: Homo sapiens
• Alignment Length: 417
• Identity: 188/417 - (45%)
• Similarity: 257/417 - (61%)
• Gaps: 38/417 - (9%)

  Fly    61 EIIVAGKYRLLKRIGNGSFGELFQAEGLKYHEKVAIKLESSTVKHPLLPREARIYGILQGGLGIP 125
            |:.|..||||.::||:||||:::....:...|:||||||....|||.|..|::.|.::|||:|||
Human     2 ELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIP 66

  Fly   126 HVKHYATEGAYNVMVMDLLGPTLEDLLNLCSRSFSMKTTLMLADQILARVELLHRRCFIHRDIKP 190
            .:|....||.||||||:||||:||||.|.|||.||:||.|:||||:::|:|.:|.:.|||||:||
Human    67 SIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKP 131

  Fly   191 DNFLMGLNRHQTQVYMIDFGLAKKFYSLRTQKHIGYTENRDLVGTARYASVRAHYA-EQSRRDDL 254
            |||||||.:....||:||||||||:...||.:||.|.||::|.|||||||:..|.. ||||||||
Human   132 DNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDL 196

  Fly   255 ESVGYLLLYFQRGRLPWQGIRAQSQAQKYEKIAEYKANIPLQQLCSGLPVEFFMYLKYCRKLHFA 319
            ||:||:|:||..|.|||||::|.::.||||:|:|.|.:.|::.||.|.|.||..||.:||.|.|.
Human   197 ESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFD 261

  Fly   320 EKPDYVYLQQLFKVLFRNQYKVCDFLFDWVVLK---RESPEQQSQQKGRERDRGGKRNVVVQKER 381
            :||||.||:|||:.||..|....|::|||.:||   ..:||...::: ||.:|          |.
Human   262 DKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRER-REHER----------EE 315

  Fly   382 HRNKDRDSDTQRCRIKNGGDLLEIEENESTTGEDPNEDKPQKKHGKACSCSYHLQKKRLQDRDRR 446
            ...:.|.|.|   |....|.......|...:..:|....|               ..|:|.....
Human   316 RMGQLRGSAT---RALPPGPPTGATANRLRSAAEPVASTP---------------ASRIQPAGNT 362

  Fly   447 APLMTERRILSGEQEQELELEL-RGSP 472
            :|    |.|...::|:::.:.| ||:|
Human   363 SP----RAISRVDRERKVSMRLHRGAP 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	151/264 (57%)
		SPS1	67..>306	CDD:223589	136/239 (57%)
CSNK1E	NP_001885.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	156/273 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	301..416		24/118 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54222
OrthoDB	1	1.010	-	-		D1097975at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.830