Protein Alignment CG12147 and Csnk1g2

DIOPT Version :10

• Sequence 1: NP_649536.1
• Gene: CG12147 / 40651
• FlyBaseID: FBgn0037325
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_598763.1
• Gene: Csnk1g2 / 103236
• MGIID: 1920014
• Length: 442
• Species: Mus musculus
• Alignment Length: 429
• Identity: 156/429 - (36%)
• Similarity: 226/429 - (52%)
• Gaps: 71/429 - (16%)

  Fly    62 IIVAGKYRLLKRIGNGSFGELFQAEGLKYHEKVAIKLESSTVKHPLLPREARIY------GILQG 120
            ::|...:|:.|:||.|:||||...:.|..:|.||||||....:.|.|..|.|.|      |....
Mouse    40 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTTGEADS 104

  Fly   121 GL---------------------GIPHVKHYATEGAYNVMVMDLLGPTLEDLLNLCSRSFSMKTT 164
            |.                     |:|.|.::...|.||.||::||||:||||.:||.|:|::||.
Mouse   105 GTGPALLGQQWLRTPSMDVSFAEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTV 169

  Fly   165 LMLADQILARVELLHRRCFIHRDIKPDNFLMGL--NRHQTQVYMIDFGLAKKFYSLRTQKHIGYT 227
            ||:|.|::.|:|.:|.:..|:||:||:|||:|.  ::.|..:::|||||||::....|:|||.|.
Mouse   170 LMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYR 234

  Fly   228 ENRDLVGTARYASVRAHYA-EQSRRDDLESVGYLLLYFQRGRLPWQGIRAQSQAQKYEKIAEYKA 291
            |::.|.|||||.|:..|.. |||||||||::|::.:||.||.|||||::|.:..::|:||.:.|.
Mouse   235 EHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKR 299

  Fly   292 NIPLQQLCSGLPVEFFMYLKYCRKLHFAEKPDYVYLQQLFKVLFRNQYKVCDFLFDWVVLKRESP 356
            ..|::.||...|.|...||:|.|:|.|.|||||.||::||..||.....|.|:.:||......:|
Mouse   300 ATPIEVLCESFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGYVFDYEYDWAGKPLPTP 364

  Fly   357 EQQSQQKGRERDRGGKRNVVVQKERHRNKDRDSDTQRCRIKNGGDLLEIEENESTTGEDPNEDKP 421
                        .|.....|..:..||:|      .:...||       :...||.|| .|.|.|
Mouse   365 ------------IGTVHPDVPSQPPHRDK------AQLHTKN-------QALNSTNGE-LNTDDP 403

  Fly   422 QKKHGKA---------------CSCSYHLQKKRLQDRDR 445
            ...|..|               |.|.:..:|::...|.:
Mouse   404 TAGHSNAPIAAPAEVEVADETKCCCFFKRRKRKSLQRHK 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	126/293 (43%)
Csnk1g2	NP_598763.1	STKc_CK1_gamma	45..359	CDD:271028	134/313 (43%)
		CK1gamma_C	359..412	CDD:463640	17/78 (22%)