Protein Alignment CG2663 and TTPAL

DIOPT Version :10

• Sequence 1: NP_649535.2
• Gene: CG2663 / 40649
• FlyBaseID: FBgn0037323
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_077307.2
• Gene: TTPAL / 79183
• HGNCID: 16114
• Length: 342
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 87/288 - (30%)
• Similarity: 137/288 - (47%)
• Gaps: 27/288 - (9%)

  Fly     7 TPDQRVSIREELREPEDPADIERDIKLIREWLETQ-PHLPKDMDDMRLTTFLRGCKFSLEKVKKK 70
            |.|.....||||:  |.|....||::.:|:.:..: |:|...:||..|..|||..||..::..:.
Human    36 TEDLVTKAREELQ--EKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQL 98

  Fly    71 LDMYYTMRNAVPEFFSNRDINREELNIVLDYVHCPTLPGITPNGRRITFIRGIDCDFQPHHILDA 135
            |..|::.|.:.||.|:|  :....|..||.......||...|.|..:..||........:.|.:.
Human    99 LVNYHSCRRSWPEVFNN--LKPSALKDVLASGFLTVLPHTDPRGCHVVCIRPDRWIPSNYPITEN 161

  Fly   136 MKVALMIGDVRLAEESVGIAGDIFILD---ASVASAAHFAKFSPTVVKKFLIAVQEAYPVKVKEV 197
            ::...:..:..:..|...:.|.:.:.|   .|::.|:|   |.|.:.||.:..:|:.:|:::|.|
Human   162 IRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASH---FGPFIAKKVIGILQDGFPIRIKAV 223

  Fly   198 HVINISPLVDTIFNFVKPFVKEKIRSRITFH-NDVESLYKVVPRDLLPNEYGGKAGGVVELNQWW 261
            ||:|...:...||..:|||:||||.:|...| :|:.||:..:||.:||.||||.||   ||
Human   224 HVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRSILPKEYGGTAG---EL---- 281

  Fly   262 KQKLVDNTQW---FKDQEDKKANESLRP 286
                 |...|   ....||....|..:|
Human   282 -----DTATWNAVLLASEDDFVKEFCQP 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2663	NP_649535.2	CRAL_TRIO_N	28..74	CDD:215024	14/46 (30%)
		CRAL_TRIO	106..249	CDD:459890	44/146 (30%)
TTPAL	NP_077307.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31
		CRAL_TRIO_N	56..102	CDD:215024	14/45 (31%)
		SEC14	128..277	CDD:469559	45/151 (30%)