Protein Alignment CG2663 and CLVS2

DIOPT Version :9

• Sequence 1: NP_649535.2
• Gene: CG2663 / 40649
• FlyBaseID: FBgn0037323
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_001010852.2
• Gene: CLVS2 / 134829
• HGNCID: 23046
• Length: 327
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 70/308 - (22%)
• Similarity: 144/308 - (46%)
• Gaps: 32/308 - (10%)

  Fly     7 TPDQRVSIREELREPEDPADIERDIKLIREWLETQPHLP-KDMDDMRLTTFLRGCKFSLEKVKKK 70
            :|:.....|.||.  |:|..:.:||:.:|:.:.|:|.:. ...||..:..|||..||...:..:.
Human     9 SPETLEKARLELN--ENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRL 71

  Fly    71 LDMYYTMRNAVPEFFSNRDINREELNIVLDYVHCPTLPGITPN----GRRITFIRGIDCDFQPHH 131
            |..|:..|....:.|.:.......:...|.    ...||...|    ||:|..:...:.|...:.
Human    72 LAQYFEYRQQNLDMFKSFKATDPGIKQALK----DGFPGGLANLDHYGRKILVLFAANWDQSRYT 132

  Fly   132 ILDAMKVALMIGDVRLAEESVGIAGDIFILDASVASAAHFAKFSPTVVKKFLIAVQEAYPVKVKE 196
            ::|.::..|:..:..:.:..:.:.|.:.|:|.|..:....:|.:|::::..:..:|:::|.:...
Human   133 LVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGG 197

  Fly   197 VHVINISPLVDTIFNFVKPFVKEKIRSRITFH-NDVESLYKVVPRDLLPNEYGGKAG----GVVE 256
            :|.:|....:..::..::||:|||.|.||..| |::.||::::..::||:|:||...    |.
Human   198 IHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGT-- 260

  Fly   257 LNQWWKQKLVDNTQWFKDQE---------DKKANESLRPGAPKTSDDL 295
                |.:.|:|: ::..|.|         .|:..:.|.|.:.|.|..:
Human   261 ----WARTLLDH-EYDDDSEYNVDSYSMPVKEVEKELSPKSMKRSQSV 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2663	NP_649535.2	CRAL_TRIO_N	28..74	CDD:215024	13/46 (28%)
		SEC14	95..250	CDD:238099	36/159 (23%)
CLVS2	NP_001010852.2	CRAL_TRIO_N	29..75	CDD:215024	13/45 (29%)
		SEC14	106..251	CDD:238099	33/144 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..327		4/17 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920