DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1172 and ubtd1a

DIOPT Version :9

Sequence 1:	NP_001246931.1	Gene:	CG1172 / 40647	FlyBaseID:	FBgn0264712	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	XP_005156917.1	Gene:	ubtd1a / 563264	ZFINID:	ZDB-GENE-070424-93	Length:	230	Species:	Danio rerio

Alignment Length:	236	Identity:	117/236 - (49%)
Similarity:	156/236 - (66%)	Gaps:	15/236 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGAC--VCRMNPDNETMSVSSASISRPASAGIAMGAARKNRPLCHETIRWRSDVPLTEGQLRSKR 63
            ||:|  |.|..        |..|.....|.|...|.  :|.||..:..:|:||.|:|||||||||
Zfish     1 MGSCFGVIRQR--------SRLSSRNAPSNGNKRGG--RNEPLKKDKPKWKSDYPMTEGQLRSKR 55

  Fly    64 DEFWDTAPAFDGRKEIWDALRAATTAAEGLDFQMAQAILDGANVSVPNGYLTECYDELGTQYKVP 128
            ||||||||||||||||||||:||..|.|..|.|:||||:|||::::|:|.|.|||||||.:|::|
Zfish    56 DEFWDTAPAFDGRKEIWDALKAAAVAIECNDHQLAQAIVDGASITLPHGSLMECYDELGNRYQLP 120

  Fly   129 IYCLSYPINIVKEENGRDSPAEYSEPVDGGTDIF-LKLRISSTMTDVKLPVYSKDTVGQCKKKLQ 192
            .||||.|:|:|.|.|..:: :|.:||.:.....| ||:|: ||..|::|.|...|::.|.||:||
Zfish   121 AYCLSPPVNLVSECNDHNA-SENAEPQEKKEKEFQLKVRL-STGKDLRLSVTMADSIRQLKKQLQ 183

  Fly   193 AAEGVDACCQRWFYSGKLLGDKVPIDECSIHQGYVVQVIVN 233
            ..|.:|...||||:|||||.||..:.:..|.:.:|:||||:
Zfish   184 IQEDIDTAHQRWFFSGKLLTDKTRLQDTKIQKDFVIQVIVS 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1172	NP_001246931.1	UBD	37..141	CDD:293064	68/103 (66%)
		UBQ	161..232	CDD:214563	32/71 (45%)
		DC_UbP_C	164..233	CDD:176389	31/68 (46%)
ubtd1a	XP_005156917.1	UBD	29..133	CDD:293064	68/103 (66%)
		UBQ	153..224	CDD:214563	33/71 (46%)
		UBQ	155..224	CDD:294102	32/69 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589261
Domainoid	1	1.000	157	1.000	Domainoid score	I4116
eggNOG	1	0.900	-	-		E1_KOG0013
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	226	1.000	Inparanoid score	I3468
OMA	1	1.010	-	-		QHG58717
OrthoDB	1	1.010	-	-		D1221075at2759
OrthoFinder	1	1.000	-	-		FOG0001843
OrthoInspector	1	1.000	-	-		otm25812
orthoMCL	1	0.900	-	-		OOG6_103755
Panther	1	1.100	-	-	O	PTHR13609
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5544
SonicParanoid	1	1.000	-	-		X1367
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800