DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1172 and ubtd1

DIOPT Version :9

Sequence 1:	NP_001246931.1	Gene:	CG1172 / 40647	FlyBaseID:	FBgn0264712	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001005656.1	Gene:	ubtd1 / 448143	XenbaseID:	XB-GENE-993611	Length:	240	Species:	Xenopus tropicalis

Alignment Length:	228	Identity:	114/228 - (50%)
Similarity:	149/228 - (65%)	Gaps:	26/228 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGACVCRMNPDNETM-SVSSASISRPASAGIAMGAARKNRPLCHETIRWRSDVPLTEGQLRSKRD 64
            ||.||.|  |..|:. |.|.||..:...||       :|.||..|..||:||.|:|:||||||||
Frog     1 MGGCVGR--PQGESQRSQSRASGQQRKRAG-------RNEPLKKERPRWKSDYPMTDGQLRSKRD 56

  Fly    65 EFWDTAPAFDGRKEIWDALRAATTAAEGLDFQMAQAILDGANVSVPNGYLTECYDELGTQYKVPI 129
            |||||||||:|||||||||:||..|.|..|.::||||:|||::::|:|.||||||||||:|::|:
Frog    57 EFWDTAPAFEGRKEIWDALKAAAFAVEANDHELAQAIVDGASITLPHGSLTECYDELGTRYQLPV 121

  Fly   130 YCLSYPINIV---KEENGRDSPAEYSEPVDGGTDIF-LKLRISSTMTDVKLPVYSKDTVGQCKKK 190
            |||:.|:|::   .||:|.|:    .||.......| ||:|: ||..||||.....||:||.||:
Frog   122 YCLAPPVNLIMERSEEDGTDA----LEPAPNTRREFQLKVRL-STGKDVKLNASMVDTIGQLKKQ 181

  Fly   191 LQAAEGVDACCQRWFY-------SGKLLGDKVP 216
            |.|.||::.|.||||:       ..:..||:.|
Frog   182 LHAVEGIEPCWQRWFFFWEASHRQNEAPGDEDP 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1172	NP_001246931.1	UBD	37..141	CDD:293064	67/106 (63%)
		UBQ	161..232	CDD:214563	28/64 (44%)
		DC_UbP_C	164..233	CDD:176389	26/60 (43%)
ubtd1	NP_001005656.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..48		22/55 (40%)
		UBD	29..131	CDD:318622	67/101 (66%)
		UBQ	155..>197	CDD:320785	23/42 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4127
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I3323
OMA	1	1.010	-	-		QHG58717
OrthoDB	1	1.010	-	-		D1221075at2759
OrthoFinder	1	1.000	-	-		FOG0001843
OrthoInspector	1	1.000	-	-		otm47993
Panther	1	1.100	-	-	LDO	PTHR13609
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5544
SonicParanoid	1	1.000	-	-		X1367
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110