DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1172 and ubtd2

DIOPT Version :9

Sequence 1:	NP_001246931.1	Gene:	CG1172 / 40647	FlyBaseID:	FBgn0264712	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001002718.2	Gene:	ubtd2 / 436991	ZFINID:	ZDB-GENE-040718-473	Length:	244	Species:	Danio rerio

Alignment Length:	233	Identity:	113/233 - (48%)
Similarity:	165/233 - (70%)	Gaps:	10/233 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGACVCRMNPDNETMSVSSASISRPASAGIAMGAARKNRPLCHETIRWRSDVPLTEGQLRSKRDE 65
            ||.||...:..:.:::.:|      ...|:|:|   :|:||..|..:|:||.|:|:|||||||||
Zfish     5 MGGCVGSHHDSSGSLNENS------DGTGVALG---RNQPLKREKPKWKSDYPMTDGQLRSKRDE 60

  Fly    66 FWDTAPAFDGRKEIWDALRAATTAAEGLDFQMAQAILDGANVSVPNGYLTECYDELGTQYKVPIY 130
            ||||||||:|||||||||:||..|.|..|.::||||:|||::::|:|.|||||||||.:|::|:|
Zfish    61 FWDTAPAFEGRKEIWDALKAAAQAFESNDHELAQAIIDGASITLPHGALTECYDELGNRYQLPVY 125

  Fly   131 CLSYPINIVKEENGRDSPAEYSEPVDGGTDIFLKLRISSTMTDVKLPVYSKDTVGQCKKKLQAAE 195
            |||.|:|:::|::..::......|...|.:..|:||: ||..|::|.|.:.|:|.|.|::||..|
Zfish   126 CLSPPVNMIEEKSESETIEVPEAPASEGQECQLRLRL-STGRDLRLAVRTSDSVQQMKRRLQTQE 189

  Fly   196 GVDACCQRWFYSGKLLGDKVPIDECSIHQGYVVQVIVN 233
            ||.|..||||:||:.|.||:.::|..|.:.|||||||:
Zfish   190 GVAATSQRWFFSGRPLTDKMKLEELKISRDYVVQVIVS 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1172	NP_001246931.1	UBD	37..141	CDD:293064	66/103 (64%)
		UBQ	161..232	CDD:214563	34/70 (49%)
		DC_UbP_C	164..233	CDD:176389	34/68 (50%)
ubtd2	NP_001002718.2	UBD	32..136	CDD:293064	66/103 (64%)
		UBQ	157..227	CDD:214563	35/70 (50%)
		UBQ	158..227	CDD:294102	35/69 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589259
Domainoid	1	1.000	157	1.000	Domainoid score	I4116
eggNOG	1	0.900	-	-		E1_KOG0013
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15484
Inparanoid	1	1.050	226	1.000	Inparanoid score	I3468
OMA	1	1.010	-	-		QHG58717
OrthoDB	1	1.010	-	-		D1221075at2759
OrthoFinder	1	1.000	-	-		FOG0001843
OrthoInspector	1	1.000	-	-		otm25812
orthoMCL	1	0.900	-	-		OOG6_103755
Panther	1	1.100	-	-	O	PTHR13609
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1367
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.770