DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1172 and Ubtd2

DIOPT Version :9

Sequence 1:	NP_001246931.1	Gene:	CG1172 / 40647	FlyBaseID:	FBgn0264712	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_776145.2	Gene:	Ubtd2 / 327900	MGIID:	2444752	Length:	234	Species:	Mus musculus

Alignment Length:	233	Identity:	114/233 - (48%)
Similarity:	165/233 - (70%)	Gaps:	10/233 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGACVCRMNPDNETMSVSSASISRPASAGIAMGAARKNRPLCHETIRWRSDVPLTEGQLRSKRDE 65
            ||.||...:..:.:::.:|      ...|:|:|   :|:||..|..:|:||.|:|:|||||||||
Mouse     1 MGGCVGAQHDSSGSLNENS------DGTGVALG---RNQPLKKEKPKWKSDYPMTDGQLRSKRDE 56

  Fly    66 FWDTAPAFDGRKEIWDALRAATTAAEGLDFQMAQAILDGANVSVPNGYLTECYDELGTQYKVPIY 130
            ||||||||:|||||||||:||..|.|..|.::||||:||||:::|:|.|||||||||.:|::|:|
Mouse    57 FWDTAPAFEGRKEIWDALKAAAHAFESNDHELAQAIIDGANITLPHGALTECYDELGNRYQLPVY 121

  Fly   131 CLSYPINIVKEENGRDSPAEYSEPVDGGTDIFLKLRISSTMTDVKLPVYSKDTVGQCKKKLQAAE 195
            ||:.|||:::|::..::......|.:.|.:..|:||: ||..|::|.|.|.|||...|::|.|.|
Mouse   122 CLAPPINMIEEKSDIETLDIPEPPPNSGHESQLRLRL-STGKDLRLVVRSTDTVFHMKRRLHATE 185

  Fly   196 GVDACCQRWFYSGKLLGDKVPIDECSIHQGYVVQVIVN 233
            ||:...||||:||:.|.||:.::|..|.:.|||||||:
Mouse   186 GVEPGSQRWFFSGRPLTDKMKLEELKIPKDYVVQVIVS 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1172	NP_001246931.1	UBD	37..141	CDD:293064	67/103 (65%)
		UBQ	161..232	CDD:214563	34/70 (49%)
		DC_UbP_C	164..233	CDD:176389	34/68 (50%)
Ubtd2	NP_776145.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..46		16/53 (30%)
		UBD	28..132	CDD:293064	67/103 (65%)
		UBQ	153..223	CDD:214563	35/70 (50%)
		DC_UbP_C	154..223	CDD:176389	35/69 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844357
Domainoid	1	1.000	157	1.000	Domainoid score	I4157
eggNOG	1	0.900	-	-		E1_KOG0013
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15484
Inparanoid	1	1.050	224	1.000	Inparanoid score	I3502
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58717
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001843
OrthoInspector	1	1.000	-	-		otm42878
orthoMCL	1	0.900	-	-		OOG6_103755
Panther	1	1.100	-	-	O	PTHR13609
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1367
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.760