DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1172 and SPAPB2B4.07

DIOPT Version :9

Sequence 1:	NP_001246931.1	Gene:	CG1172 / 40647	FlyBaseID:	FBgn0264712	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_593893.1	Gene:	SPAPB2B4.07 / 2543223	PomBaseID:	SPAPB2B4.07	Length:	239	Species:	Schizosaccharomyces pombe

Alignment Length:	260	Identity:	60/260 - (23%)
Similarity:	106/260 - (40%)	Gaps:	50/260 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGACVCRMNPDNETMSVSSASISRPASAGI-AMGAARKNRPLCHETIRWRSDVPLTEGQLRSKRD 64
            ||.|:    ..|:...|::....:|:.:.| .:.......||            ||:.::..:|:
pombe     1 MGQCL----SGNQVAGVANNGGEQPSGSNILRLPKLYTPNPL------------LTKEEVEVRRN 49

  Fly    65 EFWDTAPAFDGRKEIWDALRAATTAAEGLDFQMAQAILDGANVSVPNGYLTE-CYDELGTQYKVP 128
            |||:|..|:.|.|||||.|....|.....:.:.|..:...|::::|...::: .||..||.|::|
pombe    50 EFWETCWAYGGSKEIWDVLHKVVTLLYEGNAEAATEMALAADLTIPENDISKGVYDSKGTFYEIP 114

  Fly   129 IYCLSYPINIVKEENGRD----------SPAEYSEPVDGGTDIFLKLR---ISSTMTDVKLPVYS 180
            ......|....:.::..|          .|.:..|..|..|.....|:   :.|::..| |..||
pombe   115 KIVARIPRAFAERKDSLDDEDDNMISSNDPTKSPEEHDTTTKSIASLKDAELDSSLETV-LIRYS 178

  Fly   181 KD------------TVGQCKKKLQ--AAEGVDACCQRWFYSGKLLGDKVPIDECSIHQGYVVQVI 231
            ||            .....|.:|:  ..|.|    ||:|:.|::|..|..:.:.....|.::|.:
pombe   179 KDDKDYSIQINPNLPFSHAKSQLEEVGLENV----QRFFFLGRVLQFKKSLSQQGWTSGMIIQAM 239

Fly 232 231
pombe 240 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1172	NP_001246931.1	UBD	37..141	CDD:293064	28/104 (27%)
		UBQ	161..232	CDD:214563	20/88 (23%)
		DC_UbP_C	164..233	CDD:176389	20/85 (24%)
SPAPB2B4.07	NP_593893.1	UBD	27..121	CDD:293064	27/105 (26%)
SPAPB2B4.07	NP_593893.1	UBQ	180..239	CDD:294102	13/62 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	52	1.000	Domainoid score	I3316
eggNOG	1	0.900	-	-		E1_KOG0013
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	56	1.000	Inparanoid score	I2029
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001843
OrthoInspector	1	1.000	-	-		oto100841
orthoMCL	1	0.900	-	-		OOG6_103755
Panther	1	1.100	-	-	LDO	PTHR13609
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5544
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.890