Protein Alignment amfra and Amfr

DIOPT Version :9

• Sequence 1: NP_998328.2
• Gene: amfra / 406442
• ZFINID: ZDB-GENE-040426-2190
• Length: 620
• Species: Danio rerio
• Sequence 2: XP_038954087.1
• Gene: Amfr / 361367
• RGDID: 1311551
• Length: 643
• Species: Rattus norvegicus
• Alignment Length: 651
• Identity: 451/651 - (69%)
• Similarity: 512/651 - (78%)
• Gaps: 45/651 - (6%)

Zfish     1 MPLLFLERFPWPSLQTYTALSALLLAGTVLSAYSTVRDSEFSSALSEGPQNEELKLENL------ 59
            ||||||||||||||:|||.||.|.|.||::|||..:...|..|...| |....|:.|.|
  Rat     1 MPLLFLERFPWPSLRTYTGLSGLALLGTIVSAYRALSQPEDGSGEPE-PLTAPLQPEALAPARLT 64

Zfish    60 --GNVATGVLLHLITDSLFVWVMVNTACCILMLIGKVIQCIVFGPLRVSEKQHLKDKFWNFIFYK 122
              |.....|..:|::|||||||:||||||:|||:.|:|||||||||||||:||||||||||||||
  Rat    65 PGGPRVRDVAQYLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYK 129

Zfish   123 FIFIFGVLNVQRVEEVVLWCLWFSMLIFLHLMVQLCKDRFEYLSFSPTTPMSSHVRVLALLVSVL 187
            |||||||||||.|||||:|||||:.|:|||||||||||||||||||||||||||.|||:||:::|
  Rat   130 FIFIFGVLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLIAML 194

Zfish   188 SCCGGLAVLCALAGHIHGMHTVAFMAAECLLVTVRTGHVIIRYSIHLWDLNHEGTWENKSSYIYY 252
            ..|.||||:|.:.|:.|||||:||||||.|||||||.|||:||.|||||||||||||.|.:|:||
  Rat   195 LSCCGLAVVCCVTGYTHGMHTLAFMAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYY 259

Zfish   253 TDFIMELAILSLDLMHHIHMLLFGNIWLSMASLVIFMQLRHLFHEVQRRIRRHKNYLRVIDNMES 317
            |||:|||.:|||||||||||||||||||||||||||||||:||||||||||||||||||:.|||:
  Rat   260 TDFVMELMLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEA 324

Zfish   318 RFAVATPEELAANNDDCAICWDSMTTARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSLNIHEGRR 382
            ||||||.||||.||||||||||||..||||||||||||||||||||||||||||||||||.:|.|
  Rat   325 RFAVATAEELAVNNDDCAICWDSMQAARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSLNIADGSR 389

Zfish   383 EREEGQREPLEDNMAAAGAADARAHINQHNHFFHFDGSRIASWLPSFSVEVMHTTNILGIAQANN 447
            .||:.|.|.|::|:....||:.|..:||||||||||||||||||||||||||||||||||.||:|
  Rat   390 AREDHQGENLDENLVPVAAAEGRPRLNQHNHFFHFDGSRIASWLPSFSVEVMHTTNILGITQASN 454

Zfish   448 SQLNGMAHQIQEMFPQVPYHLILQDLQLTRSVEVTTDNILEGRIQVPFPTQ-------------- 498
            ||||.||||||||||||||||:|||||:|||||:|||||||||||||||.|
  Rat   455 SQLNAMAHQIQEMFPQVPYHLVLQDLQMTRSVEITTDNILEGRIQVPFPVQRSDSLRPALNSPVE 519

Zfish   499 -------------STDRTPIQMNAASEDGAGASSGSEVAAPEAEDFEVRGSRFSKSADERQRMLM 550
                         .|:|.|:.::...|:....|. .|:...|.||||.||||||||||||||||:
  Rat   520 RPGTDLEEGEASVQTERVPLDLSPRLEETLDFSE-VELEPVEVEDFEARGSRFSKSADERQRMLV 583

Zfish   551 QRKEELLLRARRRYLHKKPEDGDAYSVLGADNDDSVPSIEDEDSDSVTLRRRRLAAAAERRILRQ 615
            |||::||.:||:|:|:|..||..|       ::..:|| |...||.||||||.||||||||:.||
  Rat   584 QRKDDLLQQARKRFLNKSSEDDGA-------SERLLPS-EGTSSDPVTLRRRMLAAAAERRLQRQ 640

Zfish   616 E 616
            :
  Rat   641 Q 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amfra	NP_998328.2	zf-rbx1	79..>375	CDD:331150	250/295 (85%)
		RING-H2_AMFR	332..375	CDD:319369	40/42 (95%)
		RING-H2 finger (C3H2C3-type)	334..371	CDD:319369	34/36 (94%)
		CUE_AMFR	451..491	CDD:270604	35/39 (90%)
Amfr	XP_038954087.1	HRD1	86..>382	CDD:227568	250/295 (85%)
		RING-H2_AMFR	339..382	CDD:319369	40/42 (95%)
		CUE_AMFR	458..498	CDD:270604	35/39 (90%)
		G2BR	575..600	CDD:375868	17/24 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194905645
Domainoid	1	1.000	472	1.000	Domainoid score	I2980
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H888
Inparanoid	1	1.050	850	1.000	Inparanoid score	I2925
OMA	1	1.010	-	-		QHG55068
OrthoDB	1	1.010	-	-		D149264at7742
OrthoFinder	1	1.000	-	-		FOG0006872
OrthoInspector	1	1.000	-	-		oto66150
orthoMCL	1	0.900	-	-		OOG6_105132
Panther	1	1.100	-	-	LDO	PTHR15067
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3836
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910