Protein Alignment amfra and hrd1

DIOPT Version :9

• Sequence 1: NP_998328.2
• Gene: amfra / 406442
• ZFINID: ZDB-GENE-040426-2190
• Length: 620
• Species: Danio rerio
• Sequence 2: NP_596376.1
• Gene: hrd1 / 2539900
• PomBaseID: SPBC17D11.02c
• Length: 677
• Species: Schizosaccharomyces pombe
• Alignment Length: 614
• Identity: 129/614 - (21%)
• Similarity: 238/614 - (38%)
• Gaps: 124/614 - (20%)

Zfish    20 LSALLLAG--TVLSAYSTVRDSEFSSALSEGPQNEELKLENLGNVATGVLLHLITDSLFVWVMVN 82
            |::|:|.|  .:||.||:......:..:|:.|                         :.:.:.:|
pombe     8 LASLVLFGLSVLLSLYSSANVYSATVMISQSP-------------------------VHITIGLN 47

Zfish    83 TACCILMLIGKVIQCIVFGPLRVSEKQHLKDKFWNFIFYKFIFIFGVLNVQRVEEVVLWCLWFSM 147
            ...|:...|...::.::||.|:..|.:.|.::||    .....|...:.|.|....:.:.:..|.
pombe    48 VCLCLFFAIANALKTLLFGSLQTFELELLYEQFW----ITLTEIMLAITVFREAISISFFMLLST 108

Zfish   148 LIFLHLMVQLCKDRFEYLSFSPTTP---MSSHVRVLALLVSVLSCCGGLAVLCALAGHIHGMHTV 209
            |:|..:...:|..|.|.|....|..   :.|.:.....::|:|.  ..|..||..:.|:....|.
pombe   109 LMFARVFHSICSFRTERLQIQLTDQRFHIFSRLTCAYFVLSILD--ASLIYLCFTSEHLGDKSTR 171

Zfish   210 AFMAAECLLVTVRTGHVIIRYSIHLWDLNH-EGTWENKSSYIYYTDFIME-LAILSLDLMHHIHM 272
            .....|..::.:.......:..|:|::..| :..|:.||:|::..:...: |.:|:..|   :.|
pombe   172 MLFVCEFSVLLLNLTIEASKLCIYLYEARHLDQVWDEKSTYLFRLEVCRDGLRLLAYSL---LFM 233

Zfish   273 LLFGNIWLSMASLVIFMQLRHLFHEVQRRIRRHKNYLRVIDNMESRFAVATPEELAANNDDCAIC 337
            ..|..:.:.:.|:   .|:...|:.:.||||.|..:.:...:|.:.:..||.|:|..::..|.||
pombe   234 YQFPYVSVPIYSI---RQMYTCFYSLFRRIREHARFRQATRDMNAMYPTATEEQLTNSDRTCTIC 295

Zfish   338 WDSM---------------------TTARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSLNIHEGR 381
            .:.|                     .|.::|||||:.|..|||:|||:..:||.||.|:   .|.
pombe   296 REEMFHPDHPPENTDEMEPLPRGLDMTPKRLPCGHILHFHCLRNWLERQQTCPICRRSV---IGN 357

Zfish   382 REREEGQREPLEDNMAAAGAADARAHINQHNHFFHFDGSRIASWLPSFSVEVMHTTNILGIAQAN 446
            :....|  .|...|:.|                     ::||:.:|: ......||.:.||..::
pombe   358 QSSPTG--IPASPNVRA---------------------TQIATQVPN-PQNTPTTTAVPGITNSS 398

Zfish   447 N------SQLNGM--------AHQIQEMFPQVPYHLILQDLQLTRSVEVTTDNILEGRIQVPFPT 497
            |      |..||:        |...|::...:|..:.|:|        ..|...:.|..::|..:
pombe   399 NQGDPQASTFNGVPNANSSGFAAHTQDLSSVIPRRIALRD--------GWTMLPIPGTRRIPTYS 455

Zfish   498 QSTDRTPIQMNAASEDGAGASSGSEVAAPEAEDFEVRGSRFSKS----ADERQRMLMQRKEELLL 558
            |||..|    |.::....|..|.|....|:..........|::.    .....|::....:.|..
pombe   456 QSTSTT----NPSATPTTGDPSNSTYGGPQTFPNSGNNPNFNRGIAGIVPPGWRLVSSNTQSLST 516

Zfish   559 RARRRYLHKKPEDGDAYSVLGADNDDSVP 587
            .:....|::.....|  :.||:...:.||
pombe   517 NSAMTSLYQNASSAD--NNLGSSLPNVVP 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amfra	NP_998328.2	zf-rbx1	79..>375	CDD:331150	76/321 (24%)
		RING-H2_AMFR	332..375	CDD:319369	21/63 (33%)
		RING-H2 finger (C3H2C3-type)	334..371	CDD:319369	19/57 (33%)
		CUE_AMFR	451..491	CDD:270604	9/47 (19%)
hrd1	NP_596376.1	HRD1	1..514	CDD:227568	122/581 (21%)
		zf-RING_2	291..351	CDD:290367	19/59 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810