DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and zgc:175107

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001107104.1	Gene:	zgc:175107 / 794317	ZFINID:	ZDB-GENE-080220-38	Length:	333	Species:	Danio rerio

Alignment Length:	214	Identity:	54/214 - (25%)
Similarity:	87/214 - (40%)	Gaps:	12/214 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 HYDDDQYVCYQGTKEEHQDLEEIELDDDPSAAVIAAAEAAAEAAQQEDLQEQEMERAAKRRSNFF 177
            |.|.|:.......|.|.|:..|:|..:.......|..|.:........|:..:    :...|.::
Zfish    21 HEDRDKQTDLTAPKVERQETNELEERNQYDKRDSAIGEKSTHTQDASLLKRPQ----SAESSGYY 81

  Fly   178 ICDECGTLFHDAFLYTEHLNGHQNRRDMNQFFPCPECPQTFNKKALLKQHRTQVHLINRRFQCTI 242
            ||.||    :.:|...::|..|:......:.|.|.:|.::|::|..||.| .:||...:.|.|..
Zfish    82 ICGEC----NKSFGLKQNLEVHKRTHTGEKPFSCQQCGKSFSQKQNLKVH-MRVHTGEKPFSCPF 141

  Fly   243 CHEAFASLGAKLRHDKAHKNERPYPCLECGMIFSSVSELQNHFSTHSKQIRKFRCEPCNMDFITR 307
            |.:.|...|....|.:.|..|..:.|..||..||....|..|...||.: :.|.|..|...|..:
Zfish   142 CGQNFTHKGNLKTHVRNHTGESAFICNLCGKSFSRKESLNTHMRIHSGE-KPFGCAQCGKTFRCK 205

  Fly   308 RGLVAHTKTAPHKRLAKYM 326
            ..|..|.:.  |.|.:.::
Zfish   206 VNLNCHMRI--HSRESSFI 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871
		C2H2 Zn finger	179..199	CDD:275368	5/19 (26%)
		C2H2 Zn finger	211..232	CDD:275368	7/20 (35%)
		C2H2 Zn finger	240..260	CDD:275368	5/19 (26%)
		zf-C2H2_8	243..313	CDD:292531	20/69 (29%)
		C2H2 Zn finger	268..288	CDD:275368	7/19 (37%)
		C2H2 Zn finger	297..316	CDD:275368	5/18 (28%)
zgc:175107	NP_001107104.1	C2H2 Zn finger	83..103	CDD:275368	6/23 (26%)
		zf-H2C2_2	95..120	CDD:290200	6/24 (25%)
		COG5048	<107..286	CDD:227381	35/120 (29%)
		C2H2 Zn finger	111..131	CDD:275368	7/20 (35%)
		zf-H2C2_2	123..148	CDD:290200	9/25 (36%)
		C2H2 Zn finger	139..159	CDD:275368	5/19 (26%)
		zf-C2H2	165..187	CDD:278523	7/21 (33%)
		C2H2 Zn finger	167..187	CDD:275368	7/19 (37%)
		C2H2 Zn finger	195..215	CDD:275368	5/21 (24%)
		C2H2 Zn finger	223..243	CDD:275368	54/214 (25%)
		C2H2 Zn finger	251..271	CDD:275368
		zf-H2C2_2	264..287	CDD:290200
		C2H2 Zn finger	279..299	CDD:275368
		zf-H2C2_2	291..316	CDD:290200
		C2H2 Zn finger	307..324	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100