DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and zbtb48

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	XP_696166.2	Gene:	zbtb48 / 567773	ZFINID:	ZDB-GENE-030131-4450	Length:	760	Species:	Danio rerio

Alignment Length:	303	Identity:	76/303 - (25%)
Similarity:	110/303 - (36%)	Gaps:	48/303 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 RNQGLPEIVCERCFSELDLATKFRERCIFSQKYLLDIIKKTSD---QSTVHV-----ELSSEPLD 101
            |.:.|.|.....|.:..:|        :||........||..:   .:.:|.     :.:|.|
Zfish   361 RKENLLEHEARNCLTRTEL--------VFSCSKCSMTFKKRQELRHHTVMHTGVMPNKCTSCP-- 415

  Fly   102 EQLIDADQLETHYDDDQYVCYQGTKEEH------------QDLEEIELDDDPSAAVIAAAEAAAE 154
            ||.:....|:.|     .:...|..:.|            .:|...|........:....|....
Zfish   416 EQFMQKRDLKIH-----MIKVHGAPKPHACPLCPKCFLSRTELRLHEASKHRGEKLFVCEECGHR 475

  Fly   155 AAQQEDLQEQEMERAAKRRSNFFICDECGTLFHDAFLYTEHLNGHQNRRDMNQFFPCPECPQTFN 219
            |:.:..||..  .:|..|....|:|..|...|......:.||..|...:.    |.|..|.:||.
Zfish   476 ASSRNGLQMH--IKAIHRNERPFVCQLCNHAFTQKANLSMHLRTHTGEKP----FQCHLCGKTFR 534

  Fly   220 KKALL-KQHRTQVHLINRRFQCTICHEAFASLGAKLRH-DKAHKNERPYPCLECGMIFSSVSELQ 282
            .:|.| |.|||  |...|.|.|..|.:.|...|..||| ...|:..||:.|..|...|.::.:|:
Zfish   535 TQASLDKHHRT--HTGERPFSCEFCEQRFTEKGPLLRHIASKHQEGRPHFCQICNKTFKAIEQLR 597

  Fly   283 NHFSTHSKQIRKFRCEPCNMDFITRRGLVAHTKTAPHKRLAKY 325
            .|...| |.:|||.|..|...|..:..|..||:.  |.|:..|
Zfish   598 VHVRRH-KGMRKFECTLCGYKFTRQAHLRRHTQI--HNRMENY 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	7/34 (21%)
		C2H2 Zn finger	179..199	CDD:275368	5/19 (26%)
		C2H2 Zn finger	211..232	CDD:275368	10/21 (48%)
		C2H2 Zn finger	240..260	CDD:275368	7/20 (35%)
		zf-C2H2_8	243..313	CDD:292531	23/70 (33%)
		C2H2 Zn finger	268..288	CDD:275368	5/19 (26%)
		C2H2 Zn finger	297..316	CDD:275368	6/18 (33%)
zbtb48	XP_696166.2	BTB	18..109	CDD:279045
		BTB	35..116	CDD:197585
		C2H2 Zn finger	324..344	CDD:275368
		zf-H2C2_2	336..359	CDD:290200
		C2H2 Zn finger	352..403	CDD:275368	9/49 (18%)
		C2H2 Zn finger	383..402	CDD:275368	2/18 (11%)
		C2H2 Zn finger	411..432	CDD:275368	6/27 (22%)
		C2H2 Zn finger	440..461	CDD:275368	2/20 (10%)
		C2H2 Zn finger	469..490	CDD:275368	5/22 (23%)
		COG5048	<495..643	CDD:227381	50/152 (33%)
		C2H2 Zn finger	498..518	CDD:275368	5/19 (26%)
		zf-H2C2_2	510..535	CDD:290200	8/28 (29%)
		C2H2 Zn finger	526..546	CDD:275368	10/21 (48%)
		zf-H2C2_2	538..562	CDD:290200	10/25 (40%)
		C2H2 Zn finger	554..571	CDD:275368	6/16 (38%)
		C2H2 Zn finger	586..603	CDD:275368	4/16 (25%)
		zf-H2C2_2	596..620	CDD:290200	10/24 (42%)
		C2H2 Zn finger	611..631	CDD:275368	6/21 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100