DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and CG1792

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	352	Identity:	89/352 - (25%)
Similarity:	147/352 - (41%)	Gaps:	63/352 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CRICANKIMGHQRDRNIFIHMRGKYLGQLKLITGVELTRNQG--LPEIVCERCFSELDLATKFRE 69
            ||.|...|. .....|:|.......|.|::::||:.|....|  ||..:|..|..:|..|..|||
  Fly     6 CRTCGLFIF-CSTPSNLFEEPNSVMLHQIEVLTGLFLLGGPGNELPPFICSPCELDLQTAIAFRE 69

  Fly    70 RCIFSQKYL--------LDIIKKTSDQSTVHVELSSEPLDEQLIDADQLETHYDDDQYVCYQGTK 126
            |.|.:||.|        .::|:..:......::.:.|..:.::||.                 ..
  Fly    70 RVIRTQKTLQESPNLGNAELIESFAVGVEKEIQYAEEVTEIEVIDL-----------------LP 117

  Fly   127 EEH--QDLEE----IELDDDPSAAVIA---------------------AAEAAAEAAQQEDLQEQ 164
            |||  ::.||    .|.::.|...|.|                     |..:.|...|...|.|.
  Fly   118 EEHLLEETEEPYEICEQNEQPQVKVPAQEKKLRRSTKTTPTVFTSVKFADNSQATRTQWSRLTED 182

  Fly   165 EMERAAK-RRSNFFICDECGTLFHDAFLYTEHLNGHQNRRDMNQFFPCPECPQTFNKKALLKQHR 228
            |:....: ||....||::||..|.....:..||..|...:.    |.|.:|.|.|....||::|:
  Fly   183 EVVALKRERRKRDCICEQCGRHFTCPSNFKLHLLRHTGVKS----FACDQCSQQFYTATLLRRHQ 243

  Fly   229 TQVHLINRRFQCTICHEAFASLGAKLRHDK-AHKNERPYPCLECGMIFSSVSELQNHFSTHSKQI 292
             ::|..|..|||..|...:::...:::|:: .|.|.:|:.|.||...|:...:|:.|..:|: .:
  Fly   244 -ELHAGNALFQCRYCEATYSNASGRIQHERMRHTNVKPFTCKECNKSFAMSGKLRTHMLSHT-GV 306

  Fly   293 RKFRCEPCNMDFITRRGLVAHTKTAPH 319
            |.|.|:.|.:.|:.|..|.:|.::..|
  Fly   307 RAFHCDSCQVSFVRRSHLTSHYRSKGH 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	26/82 (32%)
		C2H2 Zn finger	179..199	CDD:275368	6/19 (32%)
		C2H2 Zn finger	211..232	CDD:275368	7/20 (35%)
		C2H2 Zn finger	240..260	CDD:275368	3/20 (15%)
		zf-C2H2_8	243..313	CDD:292531	19/70 (27%)
		C2H2 Zn finger	268..288	CDD:275368	6/19 (32%)
		C2H2 Zn finger	297..316	CDD:275368	6/18 (33%)
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	26/74 (35%)
		C2H2 Zn finger	198..218	CDD:275368	6/19 (32%)
		C2H2 Zn finger	226..243	CDD:275368	6/16 (38%)
		C2H2 Zn finger	254..275	CDD:275368	3/20 (15%)
		zf-C2H2	281..303	CDD:278523	6/21 (29%)
		C2H2 Zn finger	283..303	CDD:275368	6/19 (32%)
		zf-H2C2_2	296..320	CDD:290200	8/24 (33%)
		C2H2 Zn finger	311..329	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.960