DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and ZIPIC

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_651765.1	Gene:	ZIPIC / 43566	FlyBaseID:	FBgn0039740	Length:	457	Species:	Drosophila melanogaster

Alignment Length:	423	Identity:	82/423 - (19%)
Similarity:	138/423 - (32%)	Gaps:	135/423 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VCRICANKIMGHQRDRNIFIHMRGKYLGQLKLITGVELTRNQGLPEIVCERCFSELDLATKFRER 70
            :|:.|..|:..:.:...|...:||:.|         ||..:..:.:...:..:.|.||.   ||.
  Fly    50 ICKKCCEKLARYHKSIQIARKLRGEIL---------ELIHSPYMSKDHKQTSYKEDDLD---RET 102

  Fly    71 CI--FSQKYLLDIIKKTSDQSTVHVELSSEPLDEQLIDADQLETHYDDDQYVCYQGTKEEHQDLE 133
            .|  |...     |::...|.....||.|......|:....:.....::::.......||..:..
  Fly   103 TISKFDGN-----IEEAQQQDEEEQELESVGTTVTLVGPAGIVEEVAEEEHTFIIKQSEEEDEFH 162

  Fly   134 EIELDDDPSAAVIAAAEAAAEA--------------------------AQQEDL----------- 161
            .::|:.|....:|...|.|.|.                          ||:||.
  Fly   163 SVDLELDIDNEIIINEEEAHEVEEVAHEIEEVAHEIEEEDLLPHDKQEAQEEDFFKEDTMSDFDE 227

  Fly   162 ---------------QEQEMERAAK------------------------RRSNF--FICDECGTL 185
                           |||:.|.:.:                        :|.:|  ::||:||..
  Fly   228 HLDGAIEYIISDGEDQEQDNESSGEYTVNIQCPSCPEKFSSRRAYNVHTKREHFPGYVCDQCGKT 292

  Fly   186 FHDAFLYTEHLNGHQNRRDMNQFFPCPECPQTFNKKALLKQHRTQVHLINRRFQCTICHEAFAS- 249
            ......:..||..|:..:.    |.||.||:.|::|..||.|... |.....:||.:|.:.|..
  Fly   293 LQSYSGFIGHLQNHEPVKQ----FACPVCPERFSRKFRLKHHMAW-HSGETPYQCDVCSKRFVHK 352

  Fly   250 ---------------------LGAKL-------RHDKAHKNERPYPCLECGMIFSSVSELQNHFS 286
                                 .|.|.       ||.::|..::|:.|..|...||.:..::.|..
  Fly   353 VALYKHKMIHDSETKRLECQVCGFKTRTKAHLERHMRSHTGDKPFACPVCNKRFSQMYNMKAHLR 417

  Fly   287 TH----SKQIRKFRCEPCNMDFITRRGLVAHTK 315
            .|    :.:.|:|.|..|...||..:...||.:
  Fly   418 EHESPGTNRHRRFHCSKCTHTFINEQNYDAHVQ 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	16/75 (21%)
		C2H2 Zn finger	179..199	CDD:275368	6/19 (32%)
		C2H2 Zn finger	211..232	CDD:275368	9/20 (45%)
		C2H2 Zn finger	240..260	CDD:275368	7/48 (15%)
		zf-C2H2_8	243..313	CDD:292531	20/102 (20%)
		C2H2 Zn finger	268..288	CDD:275368	5/19 (26%)
		C2H2 Zn finger	297..316	CDD:275368	6/19 (32%)
ZIPIC	NP_651765.1	C2H2 Zn finger	286..306	CDD:275368	6/19 (32%)
		C2H2 Zn finger	314..334	CDD:275368	9/20 (45%)
		zf-H2C2_2	327..351	CDD:290200	8/24 (33%)
		C2H2 Zn finger	342..391	CDD:275368	7/48 (15%)
		zf-H2C2_2	383..408	CDD:290200	7/24 (29%)
		C2H2 Zn finger	399..419	CDD:275368	5/19 (26%)
		C2H2 Zn finger	432..449	CDD:275368	5/16 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100