DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and CG17802

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_650659.2	Gene:	CG17802 / 42143	FlyBaseID:	FBgn0038549	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	441	Identity:	99/441 - (22%)
Similarity:	158/441 - (35%)	Gaps:	126/441 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CRICANKIMGHQRDRNIFIHMRGKYLGQLKLITGVELTRNQGLPEIVCERCFSELDLATKFRERC 71
            ||:|.:.|. .|...||| ....|.:.|:.|:||:.||.:..:|..:|..|...|..|..||:.|
  Fly     5 CRLCGDLIY-TQNPVNIF-DENSKMVRQIALVTGLWLTDHSKMPRNMCSCCLLSLKSAIAFRQAC 67

  Fly    72 IFSQKYLL----------------------------------------------------DIIKK 84
            |.:...|.                                                    |:.||
  Fly    68 IKTNNRLTIQRRSVEAKDDGCWADPLSDAHEGLKINDAEVEQEVLYEVSYADNEGLEEDHDLYKK 132

  Fly    85 TSDQSTVHVELSSEPL----------DEQ--------LIDADQLETHYDD--DQYVCYQGTKEE- 128
            ..::|.|:.....|.:          |||        ::|.   :|.:||  :...|.:...:|
  Fly   133 EEEESEVNENKEFEDIACEIPFSKEDDEQEQQQEYEDMVDK---KTGHDDGEESQECEESQPDEE 194

  Fly   129 -----HQDLEEIELDD-----------DPSAAVIAAAEAAA-EAAQQEDLQEQE----------- 165
                 .:|.||.:.||           |..|..::..||.: ::|..||.:.:.
  Fly   195 ESQQNEEDEEESQEDDDELWQNEDGDSDTDADSMSDIEATSRQSALDEDKKPRRKYTKRSSPKND 259

  Fly   166 ----MERAAKRRSNFF-----ICDECGTLFHDAFLYTEHLNGHQNRRDMNQFFPCPECPQTFNKK 221
                ::.|.|:|..:.     |||.||..|.|...:..|:..|...:.    |.||||.|....:
  Fly   260 DTDFLKPAKKKRKTYISQKVHICDHCGKKFTDKGNFNLHVLRHSGVKP----FECPECGQKEFNR 320

  Fly   222 ALLKQHRTQVHLINRRFQCTICHEAFASLGAKLRHD-KAHKNERP---YPCLECGMIFSSVSELQ 282
            .:|..|....|...:.:.|..|.|.|.....:.||: :.|:|::.   :.|..|...:.|..:..
  Fly   321 YILNIHIRVKHRGEKPYACQFCDERFVHSTMRSRHENRVHRNKKTPKNFKCNYCDKRYESNYQRA 385

  Fly   283 NHFSTHSKQIRKFRCEPCNMDFITRRGLVAHTKTAPH--KRLAKYMQDEFD 331
            .|...|:.: |.|.||.|.:.|.....|..|.::..|  |.:|...:.|.|
  Fly   386 KHEVVHTGE-RNFHCEVCKVSFTRNSNLKTHYRSRQHQNKLIAMSAKSEID 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	25/124 (20%)
		C2H2 Zn finger	179..199	CDD:275368	7/19 (37%)
		C2H2 Zn finger	211..232	CDD:275368	7/20 (35%)
		C2H2 Zn finger	240..260	CDD:275368	6/20 (30%)
		zf-C2H2_8	243..313	CDD:292531	19/73 (26%)
		C2H2 Zn finger	268..288	CDD:275368	4/19 (21%)
		C2H2 Zn finger	297..316	CDD:275368	6/18 (33%)
CG17802	NP_650659.2	zf-AD	4..74	CDD:285071	24/70 (34%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..331	CDD:275368	7/20 (35%)
		C2H2 Zn finger	339..360	CDD:275368	6/20 (30%)
		C2H2 Zn finger	371..388	CDD:275370	3/16 (19%)
		zf-met	398..421	CDD:289631	6/22 (27%)
		C2H2 Zn finger	399..417	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.960