DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and CG17803

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001303488.1	Gene:	CG17803 / 42141	FlyBaseID:	FBgn0038547	Length:	587	Species:	Drosophila melanogaster

Alignment Length:	438	Identity:	91/438 - (20%)
Similarity:	151/438 - (34%)	Gaps:	133/438 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ADVCRICANKIMGHQRDRNIFIHMRGKYLGQLKLITGVELTRNQG---LPEIVCERCFSELDLAT 65
            |..||.|...|..|:..::::..:....|..:|:||||.:  .||   ||..:|..|...::.:.
  Fly    83 ASKCRTCFRIISRHEDAQDLYDRVNIALLHHIKVITGVWI--QQGVKELPHHICSTCQETVNKSM 145

  Fly    66 KFRERC--------IFSQKYLLDIIKKTSDQSTVHV----------------ELSSE--PLDEQL 104
            :||.:|        ..::||.:.|..:..:....:|                :.|||  |..|.:
  Fly   146 EFRAKCQQVDKKLRQTTEKYNIQICDEEMESELENVLYEESAQQAKGVVGLEDFSSELLPDSEGV 210

  Fly   105 IDADQLETHYDDDQYVCYQGTKEEHQDLE-----EIELDDDPSA--------------------- 143
            :|.|......:..|:    ...|:..||:     :..|:.:.|.
  Fly   211 LDEDDFPLDAEPTQF----SLSEDELDLDRDTEKDFALEQNKSCNEIISIRKCKTKEEIGKVDHG 271

  Fly   144 -----AVIAAAEAAAEAA--------QQEDLQEQEMERAAKRRSNF------FICDECGTLFHDA 189
                 .|:....:..|.|        ::..|:....|:..:||...      ::||:||..|...
  Fly   272 AKVYKVVLGEYNSLKETAPKYSLSLPKKPQLRVSPEEKNRRRRERIQAKPLNYVCDKCGHTFRQR 336

  Fly   190 FLYTEHLNGHQNRRDMNQFFPCPECPQTFNKKALLKQHRTQVHLINRRFQCTICHEAFASLGAKL 254
            .....||..|...::    |.|||||:.|........|...:|.....|.|..|:|:||:..::.
  Fly   337 SQLQMHLLRHNRAKN----FECPECPKKFYDLYTRNIHVRALHKGEHPFPCNHCNESFANASSRH 397

  Fly   255 RHDK-------------------------------------------AHKNERPYPCLECGMIFS 276
            ||::                                           .|...||:.|..|.|.|:
  Fly   398 RHERDVHGAGNRIRTRVKSKEEGSSRHYCTQCTKSYTSKKGLVLHMNFHNGSRPFQCKICQMKFA 462

  Fly   277 SVSELQNHFSTHSKQIRKFRCEPCNMDFITRRGLV----AHTKTAPHK 320
            ..|.::.|.:.|.|  ...||:.|...|:.|..|.    .||...||:
  Fly   463 DPSAMKRHQALHDK--FPIRCDICLKGFLLRSQLTKHQDVHTGMHPHR 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	22/84 (26%)
		C2H2 Zn finger	179..199	CDD:275368	7/19 (37%)
		C2H2 Zn finger	211..232	CDD:275368	7/20 (35%)
		C2H2 Zn finger	240..260	CDD:275368	7/62 (11%)
		zf-C2H2_8	243..313	CDD:292531	23/116 (20%)
		C2H2 Zn finger	268..288	CDD:275368	6/19 (32%)
		C2H2 Zn finger	297..316	CDD:275368	7/22 (32%)
CG17803	NP_001303488.1	zf-AD	86..160	CDD:214871	20/75 (27%)
		COG5048	<323..528	CDD:227381	46/192 (24%)
		zf-C2H2	324..346	CDD:278523	7/21 (33%)
		C2H2 Zn finger	326..346	CDD:275368	7/19 (37%)
		C2H2 Zn finger	354..375	CDD:275368	7/20 (35%)
		C2H2 Zn finger	383..401	CDD:275368	7/17 (41%)
		C2H2 Zn finger	426..446	CDD:275368	0/19 (0%)
		C2H2 Zn finger	454..474	CDD:275368	6/19 (32%)
		C2H2 Zn finger	481..501	CDD:275368	5/19 (26%)
		C2H2 Zn finger	509..528	CDD:275368	91/438 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050