DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and CG14710

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_650092.4	Gene:	CG14710 / 41393	FlyBaseID:	FBgn0037920	Length:	415	Species:	Drosophila melanogaster

Alignment Length:	413	Identity:	91/413 - (22%)
Similarity:	159/413 - (38%)	Gaps:	122/413 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CRICANK--------IMGHQRDRNIFIHMRGKYLGQLKLITGVELTRNQGLPEIVCERCFSELDL 63
            ||||...        :.|.:.:.:    :|.|    |:|...:.:.::..|||..|..|...:.:
  Fly    10 CRICLGDFEESQMICLFGDKGESD----LRKK----LELCCRIRVRQSPQLPEKACNSCCEFVQM 66

  Fly    64 ATKFRERCIFSQKY-------LLDIIKKTSD-------QSTVHVELSSEPLDEQLIDADQLETHY 114
            ...||:.|:.||.|       ..:.:.:.||       ...:|::|.:|..:::.|.|.:.....
  Fly    67 WFNFRQMCLNSQVYWETSSSERPEALAQASDAEYMLYLYENLHLKLGTENQEKEEITAIEEGDEQ 131

  Fly   115 DDDQYVCYQGTKEEHQDL------EEIELDDDPSA-----AVIAAAEAAAEAAQQEDLQE----- 163
            .:||       .:|..|.      |.||.|::|:.     .:|:..::..:..|.|:|.:
  Fly   132 QEDQ-------SQEVLDFNGFIINESIEEDEEPNTESPEQILISHMDSYVDDQQMEELIDDKGEL 189

  Fly   164 -QEMERA--------------------------------------------------AKRRSN-- 175
             :|:..|                                                  ||.|.|
  Fly   190 VEELSNANTFYEVEYGDEELLMSSAPSPHPSFKMDKQKPGRPRKPDAELKFKRKDINAKERGNQP 254

  Fly   176 ------FFICDECGTLFHDAFLYTEHLNGHQNRRDMNQFFP--CPECPQTFNKKALLKQHRTQVH 232
                  .|:|..||.:|:...::|.|:..|      :::.|  |..|.::|.:...|:.| .:.|
  Fly   255 KCKEEEKFMCILCGNVFYKKSVFTAHMMTH------SEYKPHQCEICNKSFRQMGELRAH-IRRH 312

  Fly   233 LINRRFQCTICHEAFASLGAKLRHDKAHKNERPYPCLECGMIFSSVSELQNHFSTHSKQIRKFRC 297
            ..:|.::|..|...|.....::||::.|.|.|||.|.|||..|:..:.|:||..:||.| :.:.|
  Fly   313 TGDRPYKCMYCDRHFYDRSERVRHERVHTNTRPYACQECGKTFTHTAILKNHILSHSAQ-KNYNC 376

  Fly   298 EPCNMDFITRRGLVAHTKTAPHK 320
            ..|...|.....|.||.:|..|:
  Fly   377 GICCKSFTLLHQLKAHLQTLTHR 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	20/87 (23%)
		C2H2 Zn finger	179..199	CDD:275368	6/19 (32%)
		C2H2 Zn finger	211..232	CDD:275368	5/20 (25%)
		C2H2 Zn finger	240..260	CDD:275368	5/19 (26%)
		zf-C2H2_8	243..313	CDD:292531	24/69 (35%)
		C2H2 Zn finger	268..288	CDD:275368	8/19 (42%)
		C2H2 Zn finger	297..316	CDD:275368	6/18 (33%)
CG14710	NP_650092.4	zf-AD	9..83	CDD:285071	20/80 (25%)
		COG5048	<261..395	CDD:227381	43/141 (30%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-C2H2	290..312	CDD:278523	5/22 (23%)
		C2H2 Zn finger	292..312	CDD:275368	5/20 (25%)
		zf-H2C2_2	304..327	CDD:290200	6/23 (26%)
		C2H2 Zn finger	320..340	CDD:275368	5/19 (26%)
		zf-H2C2_2	335..357	CDD:290200	12/21 (57%)
		C2H2 Zn finger	348..368	CDD:275368	8/19 (42%)
		C2H2 Zn finger	376..395	CDD:275368	6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960