DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and CG31388

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster

Alignment Length:	433	Identity:	90/433 - (20%)
Similarity:	151/433 - (34%)	Gaps:	126/433 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VCRICANKIMGHQRDRNIFIHMRGKYLGQLKLITGVELTRNQGLPEIVCERCFSELDLATKFRER 70
            :||.| :::......:|:|.......|.|::.:|.::|..:..||..:|:.|..:|.:|..||..
  Fly     4 ICRTC-SRMADPAVAKNLFDPSSSSVLRQIETLTNLQLKEDGKLPRFMCQDCQHDLQIAIDFRRV 67

  Fly    71 CIFSQKYLLDIIKKTSDQSTVHVELSSEPLDEQLID---------------ADQLETHYDDD--- 117
            ||.:|: ||::..:..::.    |.:.|.|.||.:|               .|:::..:|.:
  Fly    68 CIEAQE-LLELQLRQVEKE----EEAFESLAEQWLDDCPDELSNLSPVLQLNDRMDFIFDPEPQD 127

  Fly   118 ---------------QYV-CYQGT---------------KEEHQDL--------EEIELDDDPSA 143
                           :|: .||..               ..||.|:        |...:|:..::
  Fly   128 KNTDELASIKTTTTTEYMNAYQSVASPQSSPELSTDSQLSNEHFDMGLSPESEPESEAIDNRDTS 192

  Fly   144 AVIAAAEAAAEAAQQEDLQEQEMERAAKRRSNFFICDECGTLFHDAFLYTEHLNGHQNRRDMNQF 208
            :....::...|....::|:..:...........|:||.|...|..|...|.|.    |..::...
  Fly   193 SSHTCSKCGLEFENVDELKLHKYHLHDIPPDTKFVCDHCDEGFRSAAALTRHC----NMINLPLT 253

  Fly   209 FPCPECPQTFNKKALLKQHRTQV-------------------------HLI----NRRFQCTICH 244
            ..|.:|...|:...||:.|:.:.                         ||:    .||.:|..|.
  Fly   254 HSCTKCKSQFHNHILLETHKQRCLRPPASQHVCHICGKHLTTAFNLKNHLVRHAGTRRHKCDQCS 318

  Fly   245 EAFASLGAKLRHDKAHKNERPYPC-LECGMIFSSVSELQNHFSTH---SKQI------------- 292
            .:|.:......|.|.|..||||.| ..||..|...|....|...|   ||:|
  Fly   319 ASFYTAAELCSHQKTHTTERPYICRYNCGKTFRFCSARSMHERVHMDASKRIYQCEYCPKSYVTP 383

  Fly   293 -------------RKFRCEPCNMDFITRRGLVAHTKTAPHKRL 322
                         |...||.|.:.|.|.:...:|.|:..||.|
  Fly   384 SECRTHQKYHNLTRDHGCEICRISFKTAKHYRSHLKSNAHKTL 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	21/73 (29%)
		C2H2 Zn finger	179..199	CDD:275368	7/19 (37%)
		C2H2 Zn finger	211..232	CDD:275368	6/45 (13%)
		C2H2 Zn finger	240..260	CDD:275368	5/19 (26%)
		zf-C2H2_8	243..313	CDD:292531	25/99 (25%)
		C2H2 Zn finger	268..288	CDD:275368	6/20 (30%)
		C2H2 Zn finger	297..316	CDD:275368	6/18 (33%)
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	21/73 (29%)
		C2H2 Zn finger	228..254	CDD:275368	8/29 (28%)
		C2H2 Zn finger	286..306	CDD:275368	2/19 (11%)
		C2H2 Zn finger	314..334	CDD:275368	5/19 (26%)
		C2H2 Zn finger	342..363	CDD:275368	6/20 (30%)
		C2H2 Zn finger	373..393	CDD:275368	0/19 (0%)
		C2H2 Zn finger	401..419	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.050