DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and Zfp819

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001014039.1	Gene:	Zfp819 / 308561	RGDID:	1309564	Length:	614	Species:	Rattus norvegicus

Alignment Length:	328	Identity:	68/328 - (20%)
Similarity:	123/328 - (37%)	Gaps:	68/328 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LADVCRICANKIMGHQRDRNIFIHMRGKYLGQLKLITGVELTRNQGLPEIVC------------E 55
            :.|.||:|                                   .|||...||            .
  Rat   223 VVDSCRLC-----------------------------------TQGLSSAVCTTHSTGERACTGN 252

  Fly    56 RCFSELDLATKFRERCIFSQKYLLDIIKKTSDQSTVHVELSSEPLDEQLIDADQLETHYDDDQYV 120
            :|.:.|...:..|:..|.||.   :.::.|.|:..  ....|...::|..:...||||     ::
  Rat   253 QCANVLSPRSPLRQHGILSQD---EPVEYTKDEKA--FTAGSASCEQQTTNTLDLETH-----FI 307

  Fly   121 CYQGTKEEHQDLEEIELDDDPSAAVIAAAEAAAEAAQQEDLQEQEME--RAAKRRSNFFICDECG 183
            |:...|   ..|::.||...|..:.........:..:........::  ..|..:...:.|.:||
  Rat   308 CHICGK---SFLQKSELSFHPGTSREETRYECPDCLKSLTTSPSSLQAHHEAHTKQKPYTCHDCG 369

  Fly   184 TLFHDAFLYTEHLNGHQNRRDMNQFFPCPECPQTFNKKALLKQHRTQVHLINRRFQCTICHEAFA 248
                .:|.|..||..|.......:.:.|.:|.:.|::|::|..|: ::|...:.:.|:.|.:.|.
  Rat   370 ----KSFSYASHLKVHLRIHTGERPYVCSDCGKAFSQKSVLTTHQ-RIHTGEKPYACSHCGKLFV 429

  Fly   249 SLGAKLRHDKAHKNERPYPCLECGMIFSSVSELQNHFSTHSKQIRKFRCEPCNMDFITRRGLVAH 313
            ......:|.:.|..|:||.|.:||.:||:.|.|..|...|:.: :.::|..|...|..:..|..|
  Rat   430 YASDLRKHSRFHTGEKPYECRDCGKVFSNKSHLPVHRRIHTGE-KPYKCRDCGKSFRRKSHLQVH 493

  Fly   314 TKT 316
            .:|
  Rat   494 GRT 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	14/85 (16%)
		C2H2 Zn finger	179..199	CDD:275368	7/19 (37%)
		C2H2 Zn finger	211..232	CDD:275368	6/20 (30%)
		C2H2 Zn finger	240..260	CDD:275368	4/19 (21%)
		zf-C2H2_8	243..313	CDD:292531	20/69 (29%)
		C2H2 Zn finger	268..288	CDD:275368	8/19 (42%)
		C2H2 Zn finger	297..316	CDD:275368	5/18 (28%)
Zfp819	NP_001014039.1	KRAB	27..81	CDD:214630
		C2H2 Zn finger	336..357	CDD:275368	0/20 (0%)
		COG5048	<346..538	CDD:227381	39/157 (25%)
		C2H2 Zn finger	365..385	CDD:275368	8/23 (35%)
		C2H2 Zn finger	393..413	CDD:275368	6/20 (30%)
		C2H2 Zn finger	421..441	CDD:275368	4/19 (21%)
		C2H2 Zn finger	449..469	CDD:275368	8/19 (42%)
		C2H2 Zn finger	477..497	CDD:275368	6/20 (30%)
		SFP1	<499..582	CDD:227516
		C2H2 Zn finger	505..525	CDD:275368
		C2H2 Zn finger	533..553	CDD:275368
		C2H2 Zn finger	561..581	CDD:275368
		zf-H2C2_2	573..598	CDD:404364
		C2H2 Zn finger	589..609	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000