DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14667 and Zfp711

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	XP_002730311.1	Gene:	Zfp711 / 302327	RGDID:	1562768	Length:	805	Species:	Rattus norvegicus

Alignment Length:	365	Identity:	74/365 - (20%)
Similarity:	124/365 - (33%)	Gaps:	92/365 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 LGQLKLITGVELTRNQGLPEIVCERCFSELDLATKFRERCIFSQKYLLDIIKKTS--DQSTVHVE 94
            :|..:::|..|.|....:..:        ||.:...||:.::.      .:|.:|  :....:.|
  Rat   259 IGGTEIVTESEYTSGHSVAGV--------LDQSRMQREKMVYM------AVKDSSQEEDDISYAE 309

  Fly    95 LSSEPLDEQLIDADQ---LETHYDDDQY------VCYQGTKEEHQDLEEIELDDDPSAAVIAAAE 150
            :|.|...|.:|..::   ||...:|...      |.|..:.:|.:.....|..........:|.|
  Rat   310 ISDELYMEVIIGEEEGNLLEIQLEDSDVNKTVSPVVYPASYDERRVSRRYEDCQATGNTFDSALE 374

  Fly   151 AAAEAAQQ-----EDLQEQEM--ERAAKRRS-------------------NFFICDECGTLFHDA 189
            ..:..|.|     :.:...::  ::..|||.                   ..:.|..|...|...
  Rat   375 NRSTTAAQYLQICDSMNTNKVLKQKIKKRRRGETRQWQTAVIIGPDGQPLTVYPCHICTKKFKSR 439

  Fly   190 FLYTEHLNGHQNRRDMNQFFPCPECPQTFNKKALLKQHRTQVHLIN------------RRF---- 238
            .....|:..|.:.. |.:.:.|.:|..|.|||.....|.....|||            ||:
  Rat   440 GFLKRHMKNHPDHL-MRKKYQCTDCDFTTNKKVSFHNHLESHKLINKVDKTHEFTEYTRRYREAS 503

  Fly   239 -----------------QCTICHEAFASLGAKLRHDKA-HKNERPYPCLECGMIFSSVSELQNHF 285
                             :|..|....|..|...||..| |....|:.|:|||..|...|||:.|.
  Rat   504 PLSSNKLILRDKEPKMHKCKYCDYETAEQGLLNRHLLAVHSKSFPHVCVECGKGFRHPSELKKHM 568

  Fly   286 STHSKQIRKFRCEPCNMDFITRRGLVAHTKT-----APHK 320
            .||:.: :.::|:.|......:..|..|.|:     .|:|
  Rat   569 RTHTGE-KPYQCQYCVFRCADQSNLKTHIKSKHGNNLPYK 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	8/47 (17%)
		C2H2 Zn finger	179..199	CDD:275368	4/19 (21%)
		C2H2 Zn finger	211..232	CDD:275368	7/20 (35%)
		C2H2 Zn finger	240..260	CDD:275368	7/20 (35%)
		zf-C2H2_8	243..313	CDD:292531	22/70 (31%)
		C2H2 Zn finger	268..288	CDD:275368	9/19 (47%)
		C2H2 Zn finger	297..316	CDD:275368	4/18 (22%)
Zfp711	XP_002730311.1	Zfx_Zfy_act	65..412	CDD:398398	29/166 (17%)
		COG5048	425..803	CDD:227381	45/185 (24%)
		C2H2 Zn finger	429..449	CDD:275368	4/19 (21%)
		C2H2 Zn finger	522..543	CDD:275368	7/20 (35%)
		C2H2 Zn finger	551..571	CDD:275368	9/19 (47%)
		C2H2 Zn finger	579..600	CDD:275368	5/20 (25%)
		C2H2 Zn finger	608..634	CDD:275368	74/365 (20%)
		C2H2 Zn finger	636..657	CDD:275368
		C2H2 Zn finger	665..685	CDD:275368
		C2H2 Zn finger	722..742	CDD:275368
		C2H2 Zn finger	750..771	CDD:275368
		C2H2 Zn finger	779..799	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100