DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and ace2

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_594109.1	Gene:	ace2 / 2541661	PomBaseID:	SPAC6G10.12c	Length:	533	Species:	Schizosaccharomyces pombe

Alignment Length:	299	Identity:	59/299 - (19%)
Similarity:	97/299 - (32%)	Gaps:	103/299 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DVCRICANKIMGHQRDRNIFIHMR--GKYLGQLKLITGVELTRNQGLPEIVCERCFSELD----- 62
            ||||        |..::..|..:.  .:|:.:.:..:.|               |...||
pombe   304 DVCR--------HTDNQKAFAKLSSPAEYVSEFEKFSSV---------------CDHGLDISNAN 345

  Fly    63 ----LATKFR-----ERCIFSQKYLLDIIKKTSDQSTVHVELSSEPLDEQLIDADQ---LETHYD 115
                |..:|.     |.||.::|....|..|..:|....:|.:...:..|:.:.|.   :...||
pombe   346 INNTLTQQFALSAPYESCIVTKKPEPCITVKEEEQLAPKIESADLSITPQVTEHDSKPPVRISYD 410

  Fly   116 DDQYVCYQGTKEEHQDLEEIELDDDPSAAVIAAAEAAAEAAQQEDLQEQEMERAAKRRSNFFICD 180
               :.|    |...|......:..:..|::....||..:                      ::|
pombe   411 ---HRC----KTRKQSTRICRIPPETMASLYCGPEADGK----------------------YVC- 445

  Fly   181 ECGTLFHDAFLYTEHLNGHQNRRDMNQFFPCPECPQTFNKKALLKQHRTQVHLINRRFQCTICHE 245
                      ||    ||               |.:...:|..::.| .|.||.:|.::|.:|..
pombe   446 ----------LY----NG---------------CNKRIARKYNVESH-IQTHLSDRPYRCDLCKA 480

  Fly   246 AFASLGAKLRHDKAHKNERPYPCLECGMIFSSVSELQNH 284
            .|.......||.:.|:|.|||.| ||...|:.:..|..|
pombe   481 GFVRHHDLKRHLRIHENGRPYVC-ECLKRFNRLDALNRH 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	16/89 (18%)
		C2H2 Zn finger	179..199	CDD:275368	4/19 (21%)
		C2H2 Zn finger	211..232	CDD:275368	4/20 (20%)
		C2H2 Zn finger	240..260	CDD:275368	5/19 (26%)
		zf-C2H2_8	243..313	CDD:292531	15/42 (36%)
		C2H2 Zn finger	268..288	CDD:275368	6/17 (35%)
		C2H2 Zn finger	297..316	CDD:275368
ace2	NP_594109.1	COG5048	45..518	CDD:227381	58/297 (20%)
		C2H2 Zn finger	448..467	CDD:275368	6/34 (18%)
		zf-C2H2	473..495	CDD:278523	5/21 (24%)
		C2H2 Zn finger	475..495	CDD:275368	5/19 (26%)
		zf-H2C2_2	487..511	CDD:290200	11/24 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050