DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and Zfx

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	XP_006528028.1	Gene:	Zfx / 22764	MGIID:	99211	Length:	832	Species:	Mus musculus

Alignment Length:	338	Identity:	67/338 - (19%)
Similarity:	110/338 - (32%)	Gaps:	108/338 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 TVHVELSSEPLDE---QLIDA-DQLETHYDDDQYVCYQGTKEEHQDLEEIELDDDPSAAVIA--- 147
            ||.: :.|||.:|   :|:|. :.:....:...|:....:::|.::|...|:.|:....||.
Mouse   296 TVDI-VESEPENEHGVELLDPNNSIRVPREKMVYMAVNDSQQEEEELNVAEIADEVYMEVIVGEE 359

  Fly   148 -AAEAAAEAAQQEDLQEQEM-------------------------------------------ER 168
             ||.|||.|..::.:::.||                                           ::
Mouse   360 DAAAAAAAAVHEQQVEDNEMKTFMPIAWAAAYGNNSDGIENRNGTASALLHIDESAGLGRLAKQK 424

  Fly   169 AAKRRS-------------------NFFICDECGTLFHDAFLYTEHLNGHQNRRDMNQFFPCPEC 214
            ..|||.                   ..:.|..||..|........|:..|.......: :.|.:|
Mouse   425 PKKRRRPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLAKKK-YRCTDC 488

  Fly   215 PQTFNKKALLKQHRTQVHLIN---RRFQCTICHEAFASLGAKLRHDKAHKNER------------ 264
            ..|.|||..|..|.....|.:   :..:|..|.:.|:..||...|...||.:.
Mouse   489 DYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMHKCKFCEY 553

  Fly   265 --------------------PYPCLECGMIFSSVSELQNHFSTHSKQIRKFRCEPCNMDFITRRG 309
                                |:.|:|||..|...|||:.|...|:.: :.:.|:.|.........
Mouse   554 ETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGE-KPYECQYCEYRSADSSN 617

  Fly   310 LVAHTKTAPHKRL 322
            |..|.||...|.:
Mouse   618 LKTHVKTKHSKEM 630

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871
		C2H2 Zn finger	179..199	CDD:275368	5/19 (26%)
		C2H2 Zn finger	211..232	CDD:275368	8/20 (40%)
		C2H2 Zn finger	240..260	CDD:275368	6/19 (32%)
		zf-C2H2_8	243..313	CDD:292531	21/101 (21%)
		C2H2 Zn finger	268..288	CDD:275368	9/19 (47%)
		C2H2 Zn finger	297..316	CDD:275368	4/18 (22%)
Zfx	XP_006528028.1	Zfx_Zfy_act	104..437	CDD:368066	26/141 (18%)
		zf-C2H2	452..474	CDD:333835	5/21 (24%)
		C2H2 Zn finger	454..474	CDD:275368	5/19 (26%)
		C2H2 Zn finger	485..509	CDD:275368	9/23 (39%)
		C2H2 Zn finger	517..537	CDD:275368	6/19 (32%)
		COG5048	570..>832	CDD:227381	18/62 (29%)
		C2H2 Zn finger	577..597	CDD:275368	9/19 (47%)
		C2H2 Zn finger	605..624	CDD:275368	4/18 (22%)
		C2H2 Zn finger	662..683	CDD:275368
		C2H2 Zn finger	691..711	CDD:275368
		C2H2 Zn finger	748..768	CDD:275368
		C2H2 Zn finger	776..797	CDD:275368
		C2H2 Zn finger	805..825	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100