DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and Zfp692

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001035776.1	Gene:	Zfp692 / 103836	MGIID:	2144276	Length:	531	Species:	Mus musculus

Alignment Length:	245	Identity:	67/245 - (27%)
Similarity:	103/245 - (42%)	Gaps:	50/245 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 TSDQSTVHVELSSEPLDEQLIDADQLETHYDDDQYVCYQGTKEEHQDLEEIELDDDPSAAVIAAA 149
            ||| :.|.:|||..|                       |...|.|. .|.:|   .|.    :.|
Mouse   266 TSD-TEVRLELSRTP-----------------------QVPAELHM-TESLE---SPG----SQA 298

  Fly   150 EAAAEAAQQEDLQE---QEMERAAKRRSNFFICD--ECGTLFHDAFLYTEHLNGHQNRRDMNQ-F 208
            ::|......||..:   :.:.:||||  ....||  .||.:|.:    .::||.|:..:.::| .
Mouse   299 QSAPNPTWDEDTAQIGLRRIRKAAKR--ELMPCDFPGCGRIFSN----RQYLNHHKKYQHIHQKS 357

  Fly   209 FPCPE--CPQTFNKKALLKQHRTQVHLINRRFQCTICHEAFASLGAKLRHDKAHKNERPYPCLEC 271
            |.|||  |.::||.|..||:| .::|...|.:.|..|..:|.:....:.|.:.|..|:|..|..|
Mouse   358 FCCPEPACGKSFNFKKHLKEH-VKLHSDTRDYICEFCARSFRTSSNLVIHRRIHTGEKPLQCEIC 421

  Fly   272 GMIFSSVSELQNHFSTHSKQIR--KFRCEPCNMDFITRRGLVAH-TKTAP 318
            |......:.|..|...|::...  :|.||.|...|.....:||| :|:.|
Mouse   422 GFTCRQKASLNWHRRKHAETAAALRFPCEFCGKRFEKPDSVVAHCSKSHP 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871
		C2H2 Zn finger	179..199	CDD:275368	7/21 (33%)
		C2H2 Zn finger	211..232	CDD:275368	10/22 (45%)
		C2H2 Zn finger	240..260	CDD:275368	4/19 (21%)
		zf-C2H2_8	243..313	CDD:292531	18/71 (25%)
		C2H2 Zn finger	268..288	CDD:275368	5/19 (26%)
		C2H2 Zn finger	297..316	CDD:275368	7/19 (37%)
Zfp692	NP_001035776.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	155..249
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	287..307		5/27 (19%)
		zf-C2H2_8	328..406	CDD:292531	25/82 (30%)
		C2H2 Zn finger	360..382	CDD:275368	10/22 (45%)
		COG5048	383..>436	CDD:227381	13/52 (25%)
		C2H2 Zn finger	390..410	CDD:275368	4/19 (21%)
		zf-H2C2_2	402..427	CDD:290200	7/24 (29%)
		C2H2 Zn finger	418..438	CDD:275368	5/19 (26%)
		C2H2 Zn finger	449..465	CDD:275368	5/15 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	474..531
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100