DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14667 and si:dkeyp-2e4.2

DIOPT Version :9

Sequence 1:	NP_001014607.1	Gene:	CG14667 / 40643	FlyBaseID:	FBgn0037317	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_001122042.1	Gene:	si:dkeyp-2e4.2 / 100149164	ZFINID:	ZDB-GENE-030131-9307	Length:	251	Species:	Danio rerio

Alignment Length:	271	Identity:	58/271 - (21%)
Similarity:	90/271 - (33%)	Gaps:	87/271 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 LTRNQGLPEIVCERCFSELDLATKFRERCIFSQKYLLDIIKKTSDQSTVHVELSSE-PLD----- 101
            |::.:|...:.|.|        .|:|.:           ..:|||||:...:...| |:.
Zfish    29 LSKTEGSAALFCRR--------LKYRVK-----------TDQTSDQSSSDTDTEDELPISTSPTP 74

  Fly   102 -EQLI-------------DADQLETHYDDDQYVC--------YQGTKEEHQDLEEIELDDDPSAA 144
             |.||             ....:..|..:..|:|        .||..:||
Zfish    75 GEDLICKLCGSEFGSNISMVRHMRIHTGETPYICEVCGKGFKRQGWLKEH--------------- 124

  Fly   145 VIAAAEAAAEAAQQEDLQEQEMERAAKR-RSNFFICDECGTLFHDAFLYTEHLNGHQNRRDMNQF 208
                               ..:....|| |.....||:|...|:.:.....|||.|:..|.
Zfish   125 -------------------FRVHTGNKRKREKRLSCDQCEMKFNSSTALRSHLNKHRGERP---- 166

  Fly   209 FPCPECPQTFNKKALLKQHRTQVHLINRRFQCTICHEAFASLGAKLRHDKAHKNERPYPCLECGM 273
            |.|.:|.:|:..:..|.||....| .:::..|.:|...|....:..:|.:.|..||||.|..||.
Zfish   167 FACVQCDKTYFNQHDLNQHLRDCH-SDKKHGCYLCGNEFTRQSSLQKHMRIHTGERPYSCPHCGK 230

  Fly   274 IFSSVSELQNH 284
            .||....::.|
Zfish   231 TFSYKHSMKMH 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14667	NP_001014607.1	zf-AD	6..80	CDD:214871	6/36 (17%)
		C2H2 Zn finger	179..199	CDD:275368	7/19 (37%)
		C2H2 Zn finger	211..232	CDD:275368	6/20 (30%)
		C2H2 Zn finger	240..260	CDD:275368	4/19 (21%)
		zf-C2H2_8	243..313	CDD:292531	14/42 (33%)
		C2H2 Zn finger	268..288	CDD:275368	6/17 (35%)
		C2H2 Zn finger	297..316	CDD:275368
si:dkeyp-2e4.2	NP_001122042.1	C2H2 Zn finger	80..100	CDD:275368	0/19 (0%)
		zf-H2C2_2	92..117	CDD:290200	3/24 (13%)
		C2H2 Zn finger	108..128	CDD:275368	5/53 (9%)
		C2H2 Zn finger	141..161	CDD:275368	7/19 (37%)
		C2H2 Zn finger	169..217	CDD:275368	11/48 (23%)
		zf-H2C2_2	209..234	CDD:290200	10/24 (42%)
		C2H2 Zn finger	225..243	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100