Protein Alignment hd and Donson

DIOPT Version :10

• Sequence 1: NP_649531.1
• Gene: hd / 40642
• FlyBaseID: FBgn0086695
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_001386195.1
• Gene: Donson / 288257
• RGDID: 1306823
• Length: 559
• Species: Rattus norvegicus
• Alignment Length: 577
• Identity: 176/577 - (30%)
• Similarity: 257/577 - (44%)
• Gaps: 114/577 - (19%)

  Fly    13 RPDDFIKLQRLKQKKNKLAARVSNNNNRRPRHQVDETDKS----KLLEAKLAQ------------ 61
            ||.:.::|:|                 :|||........:    .|..|.||.
  Rat    14 RPPEVVRLRR-----------------KRPRDHGTAVSSALPEPALRRAALAAGLPLRPFPTAGG 61

  Fly    62 --------KRKNPFAKSTADAKKLRVD--PQLADLEPVVTASSCFVRETPTR---PAPAKFVLQK 113
                    .|:||||         |:|  |::||..|          |.|.|   .||...:...
  Rat    62 RGGATTTIARRNPFA---------RLDNRPRVADEAP----------EEPLRGPQGAPGPLLDSN 107

  Fly   114 YDPQAFAKLFQHPQINAEDEDDAELAARQKHT-----AHLPVDWSLKTRARFFCPTELP---AIQ 170
            .:.....:...|.:...|.....::...:..|     ..||||||:|||..|  .:..|   |..
  Rat   108 GENNLLWEEASHERTVTELSQSQQVTLSESDTWSSDGTELPVDWSIKTRLLF--TSSQPFSWAEH 170

  Fly   171 LKTSQLASGLTSFVRCMDPQRTESTLD--ISDATR--FNQCNYYWQHPHLPWLTLYPRTAKENVG 231
            ||..:.|.||....|..:....:|..|  :|...|  |.|...||.||...||.|:||...:...
  Rat   171 LKAQEEAQGLVQHCRATEVTLPQSIPDPKLSTVLRCAFQQTLVYWLHPAFSWLPLFPRIGADRKM 235

  Fly   232 VV------VGERERKALAEEWDFSFRGLFQLLRARQCPYFYLCANTFTVLFRAAGVGGRPESHAL 290
            ..      ..|..:.||..:|..||..|:.||:.:.|||||:|:..|||||||||:.|.....||
  Rat   236 AAKTSPWSTDESLQHALMSDWSVSFTSLYNLLKTKLCPYFYVCSYQFTVLFRAAGLAGSSVITAL 300

  Fly   291 VTPSTRGMRQALRQEGIEFSMPLKSDNSGNAHDNSFNEESTTTSLGPEAGEDAPPPAQEDEDDDE 355
            :||:|||:|:|::.||||||:||..:   :.|.....|.|..:       |:....:.|||::..
  Rat   301 ITPTTRGLREAMKSEGIEFSLPLLEE---SGHKEKVREPSLES-------EEEQAVSDEDEEESL 355

  Fly   356 DWLESLGVDERELRRIQSSHARKQQAAEMREDFSDNSLLLVDGVECQGFFSYLLNAKSAISTVGR 420
            .|||.:||.::..:....|...:::..|::.|....|::||.|:......::|:|.||.::|.|.
  Rat   356 SWLEEIGVQDQIKKPDLISVKLRKEKHEVQMDHRPESVVLVKGLNTFKLLNFLINCKSLVATSGA 420

  Fly   421 LAGVPPTLLSPVAFPKATMQHLVPRSKKVRLDGV----DYFSIDIKGLILPTFLPSVAELL-SET 480
            .||:||||||||||..|:||.|..||..|:...:    |.||::|.|.::|..|.|||.|| |..
  Rat   421 QAGLPPTLLSPVAFRGASMQMLKARSINVKTQALFGYRDKFSLEITGPVMPHALHSVAMLLRSSQ 485

  Fly   481 RQMFSSTLASSINTLAFSKATQKLLETPETPQSDAEGEDAAGQVFGEQNLSECGLLP 537
            |..||:.|.:...|..|:      :..|...:.|.:|        ..::|:.|||.|
  Rat   486 RGSFSAGLYAHEPTAVFN------VGLPLDKELDRKG--------AHKDLANCGLHP 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hd	NP_649531.1	None
Donson	NP_001386195.1	PHA03378	<6..102	CDD:223065	27/123 (22%)