DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cerk and LCBK1

DIOPT Version :9

Sequence 1:	NP_649530.2	Gene:	Cerk / 40640	FlyBaseID:	FBgn0037315	Length:	687	Species:	Drosophila melanogaster
Sequence 2:	NP_001031929.4	Gene:	LCBK1 / 832411	AraportID:	AT5G23450	Length:	778	Species:	Arabidopsis thaliana

Alignment Length:	817	Identity:	171/817 - (20%)
Similarity:	303/817 - (37%)	Gaps:	235/817 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PAGRSSTSAGDFVAPISSTSASKFTPC-----------SASDHNVLLNNFQLKKK--SYRV---- 54
            |..:.|.....|.:.|::..:.:.:|.           ::|....:.|:.|:|.|  .:|:
plant    17 PQAQQSLRRLGFCSQIATGGSQQSSPIVFPEKRNKKVKASSRRGEVTNDPQVKPKPDEHRIDIGG 81

  Fly    55 ----------LLHGQQLVWERLQKIKQSPQGNEAKAPLPPD------------SPAQPGGICSYG 97
                      |::..:||.:: :|........|.:.|...|            |.|...|
plant    82 GDEKSDLLGSLVYAGKLVLDK-RKSASGKDATEIQQPAATDISIKKAVDAKLTSSALVWG----- 140

  Fly    98 PQSHVLHLDDVVSIRSGDTKASSLKPPSPPGSERSSG--CSGDVAQGKPTSQYL--TINYAMRLS 158
              |.:|.|:||||: :.:.........:.|..:.|.|  |.....:.:...:::  |:..|::..
plant   141 --SDMLQLNDVVSV-TYNVGLRHFTVHAYPIGKGSCGLSCFTKPKRSRKDFRFVAPTVEEAVQWV 202

  Fly   159 KSQTDCNRWELRRLTFFNSDPYIV---RQWDQELQIRLHSSSPTRMRVR-----RLLVFINPYGG 215
            .|..|       :..|.|..|:.:   :|...|| ..:...:|..:..|     ::||.:||..|
plant   203 ASFGD-------QQCFINCLPHPLVAKKQASSEL-FSVPIDTPPELVFRCKSAPKMLVILNPRSG 259

  Fly   216 RKAGAQTYERHVRPIFQLAGVDATCITTQRANQVKDILLSHDLGV-YDAVCCVGGDG-------- 271
            .....:.:...|.|||:|||:....:.|.:|...:::..:.|:.: .|.:.||||||
plant   260 HGRSIKVFHNVVEPIFKLAGIKMEVVKTTKAGHARELASTVDINLCSDGIICVGGDGIINENSLG 324

  Fly   272 -------TVAEVINGLIFRQMRELGLDEQRPPYIPRPALPVGVIPAGSTDTIAYSMHGTADVRTA 329
                   |..:|:|||:.|...:.|:           ::|:|::||||.:::.:::.|..|..:|
plant   325 RLRWIQKTAFDVLNGLLTRSNPKEGV-----------SIPIGIVPAGSDNSLVWTVLGVRDPISA 378

  Fly   330 AIHVILGQHRGLDVCSVS---NGQSLLRFCASVLSYGYLGDVAAQSENY-RWMGPRRY------- 383
            |:.::.|.....||.:|.   .|  ::.|..:|..||::.||...||.| :..||.||
plant   379 ALSIVKGGLTATDVFAVEWIHTG--IIHFGMTVSYYGFVSDVLELSEKYQKRFGPLRYFVAGFLK 441

  Fly   384 -----EYSGVKAFLNNRGYDAE--LRMLEE--------PDLLLTTPLEDIPQ-----SPDSVC-- 426
                 :||....:|..:..|||  :|:.:|        .|::..:..|..|:     |.||:.
plant   442 FMCLPKYSYEVEYLPAQKEDAEGKIRLEKEAVDMQDLYTDVMRRSSREGFPRASSLSSIDSIMTP 506

  Fly   427 SLGE-SVPSVCYANCQRCSFASSIQEQRSSLFIQEESKEAERNQQVETEDSHLAASEAALLRPRP 490
            |:|| ...|..:|:.:...:...|..:...|      ....|:...|.|..|..|.......||.
plant   507 SVGELDTCSSTHASTEPSEYVRGIDPKMKRL------SSGRRDVTAEPEVIHPQAQSTTPNWPRT 565

  Fly   491 R-----------------------------------------PG--------------------N 494
            |                                         ||                    :
plant   566 RSKSRMDKGWMGLTSVQDPPTRCSWGNTGGQDREDISSTVSDPGPIWDAGPKWDTEPSAWDVENS 630

  Fly   495 LRLP-------TG-SISSMRNLGNDQWKVVRGNFFMICGANITCACARSPNGISRYSHLGDGCLD 551
            :.||       || ...|:..:..|:|...:|:|..|...|..|...:|...::..|...||.:|
plant   631 IELPGPPEDIETGLRKQSITPIFEDKWVSRKGHFLGIMVCNHACRTVQSSQVVAPNSEHDDGTMD 695

  Fly   552 LILVKKTSLLNNVRF--LLNTAGRSGDIRNLPFVEVYRTREFRFRTFSASEEDYSLAGSCQPITP 614
            ::||.....|..:||  ||.|    |...:||:||..:.:..:.:....:.:...:.|
plant   696 MLLVHGCGRLRLLRFFILLQT----GRHLSLPYVECVKVKSVKIKAGKNTHDSCGIDG------- 749

  Fly   615 PEEMTAHSSSTEFSSWNCDGEVVTDLDITMRSHCQLI 651
             |....|            |||::.:   :...|:||
plant   750 -ELFALH------------GEVISTM---LPEQCRLI 770

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cerk	NP_649530.2	PLN02204	157..658	CDD:215126	137/624 (22%)
LCBK1	NP_001031929.4	DAGK_cat	249..395	CDD:279163	42/156 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1597
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12358
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.870