DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cerk and Agk

DIOPT Version :9

Sequence 1:	NP_649530.2	Gene:	Cerk / 40640	FlyBaseID:	FBgn0037315	Length:	687	Species:	Drosophila melanogaster
Sequence 2:	NP_076027.1	Gene:	Agk / 69923	MGIID:	1917173	Length:	421	Species:	Mus musculus

Alignment Length:	342	Identity:	73/342 - (21%)
Similarity:	139/342 - (40%)	Gaps:	43/342 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 QELQIRLHSSSPTRMRVRRLLVFINPYGGRKAGAQTYERHVRPIFQLAGVDATCITTQRANQVKD 251
            ||.|:..:...|...:|::..||:||...:......:|::..||..|:|:|.|.:.|....|.|.
Mouse    44 QEAQVFGNQLIPPNAQVKKATVFLNPAACKGKARTLFEKNAAPILHLSGMDVTVVKTDYEGQAKK 108

  Fly   252 ILLSHDLGVYDAVCCVGGDGTVAEVINGLIFRQMRELGLDEQRPPYIPRPALPVGVIPAGSTDTI 316
            :|  ..:...|.:...|||||:.||:.| :.|:..|....:          :|:|.||.|.|.::
Mouse   109 LL--ELMESTDVIIVAGGDGTLQEVVTG-VLRRTDEATFSK----------IPIGFIPLGQTSSL 160

  Fly   317 AYSMHGTA-----DVRTAAIHVILGQHRGLDVCSVSNGQSLLRFCASVLSYGYLGDVAAQSENYR 376
            ::::...:     .:..|.:.::.|:...|||..:...:....:..:.|.:|...|...:...|.
Mouse   161 SHTLFAESGNKVQHITDATLAIVKGETVPLDVLQIKGEKEQPVYAMTGLRWGSFRDAGVKVSKYW 225

  Fly   377 WMGPRRYEYSGVKAFLNNRGYDAELRMLEEPDLLLTTPLEDIPQSPDSVCSLGESVPSVCYANCQ 441
            ::||.:.:.:...:.|.      |.....:..:..|.|.|..|..|:      |:.|
Mouse   226 YLGPLKTKAAHFFSTLQ------EWPQTHQASISYTGPRERPPIEPE------ETPP-------- 270

  Fly   442 RCSFASSIQEQRSSLFIQEESKEAERNQQVETEDSHLAASEAALLRPRPRPGNLRLPTGSISSMR 506
            |.|....|..:.:|.:.|.:...:........:|..|:..|.::     ...|.:|...|.....
Mouse   271 RPSLYRRILRRLASFWAQPQDASSREVSPEVWKDVQLSTIELSI-----TTRNTQLDLMSKEDFM 330

  Fly   507 NLGNDQWKVVRGNFFMI 523
            |:..:...|.:|:|.:|
Mouse   331 NICIEPDTVSKGDFIII 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cerk	NP_649530.2	PLN02204	157..658	CDD:215126	73/342 (21%)
Agk	NP_076027.1	Hydrophobic. /evidence=ECO:0000250\|UniProtKB:Q53H12	15..31
		DAGK_cat	62..195	CDD:279163	37/145 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	252..271		7/32 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1597
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810