Protein Alignment Cerk and Sk2

DIOPT Version :9

• Sequence 1: NP_649530.2
• Gene: Cerk / 40640
• FlyBaseID: FBgn0037315
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_647762.3
• Gene: Sk2 / 326219
• FlyBaseID: FBgn0052484
• Length: 661
• Species: Drosophila melanogaster
• Alignment Length: 691
• Identity: 178/691 - (25%)
• Similarity: 265/691 - (38%)
• Gaps: 192/691 - (27%)

  Fly    24 STSASKFTPCSASD----HNV--LLNNFQLKKKS--YRVLLHGQQLVWERLQKIKQSPQGNEAKA 80
            |:::|:.||....|    |:|  .....|.||.|  :||.|.......:|     :||.|:..|
  Fly    12 SSASSRATPPGTQDADEGHDVSDTFYTSQRKKGSHVFRVRLDATGFTLQR-----ESPGGSIVK- 70

  Fly    81 PLPPDSPAQPGGICSYGPQSHVLHLDDVVSIR------------SGDTKASSLKPPSPPGSERS- 132
                              :.|| .:.|:|..|            ||....||..|.||..|...
  Fly    71 ------------------EQHV-RISDIVGARCMRPKKSRRLAMSGACACSSGNPNSPAISASGD 116

  Fly   133 --------SGCSGD-----VAQGKPTSQYLTINYAMRLSKSQTDCNRWELRR------LTFFNSD 178
                    |.||.:     .:.|...|.:|.: :|..|.|...   |.||.|      |.|.:.|
  Fly   117 HHRPATTPSKCSTNSRDNIPSDGGDVSAFLYV-FAYVLKKRSL---RSELHRERTVLTLRFRSFD 177

  Fly   179 PY-----IVRQWDQELQIRLHSS------SPT-RMRVRRLLVFINPYGGRKAGAQTYERHVRPIF 231
            .:     ...:|.:.|:.:||.:      :|| ..|.||:||.:||..|.....:.:..||.|:.
  Fly   178 TFEDNMREADRWYRSLRWQLHRTLEEIFVAPTVDERRRRVLVLLNPKSGSGDAREVFNMHVTPVL 242

  Fly   232 QLAGVDATCITTQRANQVKDILLSHDLGVYDAVCC---VGGDGTVAEVINGLIFRQMRELGLDEQ 293
            ..|.|......|:.:|...:.|.:..|   ||.||   |||||...|::|||:.||.....|
  Fly   243 NEAEVPYDLYVTKHSNFAIEFLSTRCL---DAWCCVVAVGGDGLFHEIVNGLLQRQDWAHVL--- 301

  Fly   294 RPPYIPRPALPVGVIPAGSTDTIAYSM-------HGTADVRTAAIHVILGQHRGLDVCSVS-NGQ 350
                   |.|.:|:||.||.:.:|.|:       :.:..|..||:.||.|:...:||..|. ..:
  Fly   302 -------PHLALGIIPCGSGNGLARSIAHCYNEPYFSKPVLGAALTVISGRSSPMDVVRVQLQSR 359

  Fly   351 SLLRFCASVLSYGYLGDVAAQSENYRWMGPRRY------------EYSGVKAFL----------N 393
            ||..|.:  :.:|.:.||..:||..|.:|.:|:            .|:|..::|          :
  Fly   360 SLYSFLS--IGWGLISDVDIESERIRMLGYQRFTVWTLYRLVNLRTYNGRISYLLTDHEVSSTHS 422

  Fly   394 NRGYDAELR------------MLEEPDLLLTTPLEDIPQSPDSVCSLGESVPSVCYANC------ 440
            ..||.|:.|            ||..|..:..:..|.:||....|.||..|:.....:.|
  Fly   423 ATGYAAQRRMQSSRSCNTHIDMLNGPAPIYHSSAEYLPQEFADVISLETSINQSFRSRCDSWLSG 487

  Fly   441 -QRCSFASSIQEQRSSLFIQEESKEAERNQQVETEDSHLAASEAALLRPRPRPGNLRLPTGSISS 504
             .|.||..||.|   |::            ....::|..|...||.|..|.:...   |...:..
  Fly   488 GSRRSFYYSISE---SIY------------HSLADESEFAGLAAASLENRQQNYG---PASELPD 534

  Fly   505 MRN-LGNDQ-WKVVRGNFFM---ICGANITCACARSPNGISRYSHLGDGCLDLILVK----KTSL 560
            :.. |..|| |.|..|.|.|   :...::...|..:|.     :.|.||.:.|||::    :..|
  Fly   535 LNEPLSEDQGWLVEEGEFVMMHAVYQTHLGIDCHFAPK-----AQLNDGTIYLILIRAGISRPHL 594

  Fly   561 LNNVRFLLNTAGRSGDIRNLP-----FVEVYRTREFRFRTF 596
            |:   ||.|.:  ||  .:||     .|:|...|.||...:
  Fly   595 LS---FLYNMS--SG--THLPESHDDHVKVLPVRAFRLEPY 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cerk	NP_649530.2	PLN02204	157..658	CDD:215126	139/524 (27%)
Sk2	NP_647762.3	PLN02958	<213..639	CDD:215517	124/461 (27%)
		DAGK_cat	216..354	CDD:279163	48/150 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447427
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1597
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681139at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12358
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R653
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.880