Protein Alignment Cerk and cerkl

DIOPT Version :10

• Sequence 1: NP_649530.2
• Gene: Cerk / 40640
• FlyBaseID: FBgn0037315
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: XP_002932061.3
• Gene: cerkl / 100487761
• XenbaseID: XB-GENE-6035280
• Length: 620
• Species: Xenopus tropicalis
• Alignment Length: 663
• Identity: 154/663 - (23%)
• Similarity: 261/663 - (39%)
• Gaps: 187/663 - (28%)

  Fly     8 AGRSSTSAGDFVAPISSTSASKFTPCSASDHNVLLNN-FQLKKKSYRVLLHGQQLVWERLQKIKQ 71
            :||||...|                  .....:||.. |.::|:|..|.|...||.|
 Frog   112 SGRSSRDPG------------------GGQPAILLRGIFHIEKRSCDVSLTCNQLQW-------- 150

  Fly    72 SPQGNEAKAPLPPDSPAQPGGICSYGPQSHVLHLDDVVSIR------SGDTKASSLKPPSPPGSE 130
                    :|:.|:||....  .::..:..:|.|.|:.|::      :|.||..:|..
 Frog   151 --------SPIQPESPGSTS--LTHQQKEEILDLRDIFSVKLKRRRSAGQTKGGTLLG------- 198

  Fly   131 RSSGCSGDVAQGKPTSQYLTINYAMRLSKSQTDCNRWELRRLTFFNSDPYIVRQWDQELQIRLHS 195
                              :||...:|..:...|      |.:...|........|.::|: .:.:
 Frog   199 ------------------ITIFLCIRKGRKLKD------RSVHLHNQSEDYCDIWFKQLK-EILN 238

  Fly   196 SSPTRMRVRRLLVFINPYGGRKAGAQTYERHVRPIFQLAGVDATCITTQRANQVKDILLSHDLGV 260
            ..|.  |.:.|.:.|||:..:...::.|..||.|:|:||.:......|..|.....:|...:|..
 Frog   239 GFPN--RPKSLKIIINPHSHKGEASKLYYEHVAPLFKLADIQTDVTETTYAGHALALLRECELQE 301

  Fly   261 YDAVCCVGGDGTVAEVINGLIFRQMRELGLDEQRPPYIPRPALPVGVIPAGSTDTIAYSMHGTAD 325
            ||.|.||||||:..||.:||:.|...:.|.:........|..:|:|:||||||:.:|||:|||..
 Frog   302 YDGVVCVGGDGSANEVAHGLLLRAQIDAGKNTDTIFTPVRAPIPLGIIPAGSTNVLAYSLHGTKH 366

  Fly   326 VRTAAIHVILGQHRGLDVCSVSNGQSLLRFCASVLSYGYLGDVAAQSENYRWM-GPRRYEYSGVK 389
            ..|||:|:|:|..:.:|.|:.|:...||||..|.: :|:.|...|.:|.:||| ..:|.|::.:|
 Frog   367 TGTAALHIIMGNIQPVDTCTFSSSNKLLRFGFSAM-FGFGGATLALAEKHRWMPSSQRREFAFLK 430

  Fly   390 AFLNNRGYDAELRMLEEPDLLLTTPLEDIPQSPDSVCSLGESVPSVCYANCQRCSFASSIQEQRS 454
            ...|.:....||..|         |:::
 Frog   431 TLANLKPESCELTFL---------PIKN------------------------------------- 449

  Fly   455 SLFIQEESK--EAERNQQVETEDSHLAASEAALLRPRPRPGNLRLPTGSISSMRNLGNDQWKVVR 517
                 ||.|  .|::|::          .:||                     |:...|.|:.::
 Frog   450 -----EEVKYRGAQKNKR----------EKAA---------------------RSGSKDPWQHIQ 478

  Fly   518 GNFFMICGANITCACARSPNGISRYSHLGDGCLDLILVKKTSLLNNVRFLLNTAGRSGDIRN--- 579
            |....:....|.|.|:.:|.|::..:.|.:|.:.|.:|:.|:....|:.|    .|...::|
 Frog   479 GQLLNVSIMAIPCLCSMAPRGLAPNTRLSNGTMALNIVRNTTRQEFVKHL----KRFATLKNPFS 539

  Fly   580 LPFVEVYRTREFR--FRTFSASEEDYSLAGSCQPITPPEEMTAHSSSTEFSSWNCDGEVV-TDLD 641
            .|||:.:...|.:  .|.:..|.:              |:....:::.:...||.||::| ...|
 Frog   540 FPFVDTFLVEEVKISLRNYGRSSQ--------------EQNGNRNTAEDICPWNIDGDLVEVSSD 590

  Fly   642 ITMRSHCQLIEVF 654
            |.:|.|.:||.::
 Frog   591 IHVRLHPELINIY 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cerk	NP_649530.2	DAGK_cat	157..658	CDD:445337	124/507 (24%)
cerkl	XP_002932061.3	DAGK_cat	140..608	CDD:445337	144/617 (23%)
		CERK_C	398..620	CDD:466025	59/307 (19%)