Protein Alignment Prosbeta7 and PSMB4

DIOPT Version :10

• Sequence 1: NP_649529.1
• Gene: Prosbeta7 / 40639
• FlyBaseID: FBgn0250746
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_002787.2
• Gene: PSMB4 / 5692
• HGNCID: 9541
• Length: 264
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 103/258 - (39%)
• Similarity: 157/258 - (60%)
• Gaps: 6/258 - (2%)

  Fly    12 MWQNGPAPGEFYNFTGGQTPVQQL-PRELTTMGPYGTKHSTASSTTGTSVLGIRYDSGVMLAADT 75
            :|..|||||:||...  .||...: |......||  ...:.....|||||||::::.||::|||.
Human    11 LWAGGPAPGQFYRIP--STPDSFMDPASALYRGP--ITRTQNPMVTGTSVLGVKFEGGVVIAADM 71

  Fly    76 LVSYGSMARYQNIERVFKVNKNILLGGSGDFADIQSIKRNIDQKMIEDQCCDDNIEMKPKSLASW 140
            |.||||:||::||.|:.:||.:.:||.|||:||.|.:|:.:.|.:|:::...|.....|:::.||
Human    72 LGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEELLGDGHSYSPRAIHSW 136

  Fly   141 MTRVLYNRRSRMNPLYIDVVVGGVDNEGTPYLANVDLRGRSYEDYVVATGFARHLAVPLVREKKP 205
            :||.:|:|||:||||:..:|:||. .:|..:|..||:.|.:||...:|||:..:||.||:||...
Human   137 LTRAMYSRRSKMNPLWNTMVIGGY-ADGESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLE 200

  Fly   206 KDRDFTAVEASELIRTCMEVLYYRDTRNISQYTVGVCSVNGCGVEGPFQVNENWTFAETIKGY 268
            |....:..||.:|:..||.||||||.|:.:::.:...:..|..:|||.....||..|..|.|:
Human   201 KQPVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEKGVEIEGPLSTETNWDIAHMISGF 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta7	NP_649529.1	proteasome_beta_type_4	60..252	CDD:239729	79/191 (41%)
PSMB4	NP_002787.2	proteasome_beta_type_4	52..247	CDD:239729	83/195 (43%)