DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta7 and psmb4

DIOPT Version :9

Sequence 1:	NP_649529.1	Gene:	Prosbeta7 / 40639	FlyBaseID:	FBgn0250746	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_005159798.1	Gene:	psmb4 / 550499	ZFINID:	ZDB-GENE-050417-333	Length:	256	Species:	Danio rerio

Alignment Length:	263	Identity:	114/263 - (43%)
Similarity:	162/263 - (61%)	Gaps:	11/263 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 NSLAQPMWQNGPAPGEFYNFTGGQTPVQQLPRELTTMGPYGTKHSTASSTTGTSVLGIRYDSGVM 70
            |.|....|:|||.||:||:|.|...        ....||  .||:.....|||||||:::..||:
Zfish     4 NGLKLNFWENGPKPGQFYSFPGSSA--------APACGP--IKHTLNPMVTGTSVLGVKFKGGVI 58

  Fly    71 LAADTLVSYGSMARYQNIERVFKVNKNILLGGSGDFADIQSIKRNIDQKMIEDQCCDDNIEMKPK 135
            :|||.|.||||:||::||.|:.|||.:.:||.|||:||.|.:|:.|:|.:|:::...|.....||
Zfish    59 IAADMLGSYGSLARFRNISRLMKVNNSTILGASGDYADYQYLKQIIEQMVIDEELLGDGHSYTPK 123

  Fly   136 SLASWMTRVLYNRRSRMNPLYIDVVVGGVDNEGTPYLANVDLRGRSYEDYVVATGFARHLAVPLV 200
            ::.||:|||:|||||:||||:..||:||..| |..:|..||..|.:||...|||||..:||.||:
Zfish   124 AIHSWLTRVMYNRRSKMNPLWNTVVIGGFYN-GESFLGYVDKLGVAYEAPTVATGFGAYLAQPLM 187

  Fly   201 REKKPKDRDFTAVEASELIRTCMEVLYYRDTRNISQYTVGVCSVNGCGVEGPFQVNENWTFAETI 265
            ||......:.|..||.|||..|::||||||.|:.:::.:.:.:.:|..:.||.....||..|..:
Zfish   188 REVIENKEEITKEEARELIERCLKVLYYRDARSYNRHEIAIVTADGVEIIGPLSSETNWDIAHLV 252

  Fly   266 KGY 268
            .|:
Zfish   253 SGF 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta7	NP_649529.1	proteasome_beta_type_4	60..252	CDD:239729	88/191 (46%)
Prosbeta7	NP_649529.1	PRE1	60..232	CDD:223711	86/171 (50%)
psmb4	XP_005159798.1	proteasome_beta_type_4	44..239	CDD:239729	92/195 (47%)
psmb4	XP_005159798.1	PRE1	44..233	CDD:223711	91/189 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590434
Domainoid	1	1.000	184	1.000	Domainoid score	I3359
eggNOG	1	0.900	-	-		E1_KOG0185
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2090
Inparanoid	1	1.050	225	1.000	Inparanoid score	I3489
OMA	1	1.010	-	-		QHG53720
OrthoDB	1	1.010	-	-		D1228942at2759
OrthoFinder	1	1.000	-	-		FOG0004376
OrthoInspector	1	1.000	-	-		oto40417
orthoMCL	1	0.900	-	-		OOG6_101718
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1012
SonicParanoid	1	1.000	-	-		X3101
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800