DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta7 and pbs-7

DIOPT Version :9

Sequence 1:	NP_649529.1	Gene:	Prosbeta7 / 40639	FlyBaseID:	FBgn0250746	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_492354.1	Gene:	pbs-7 / 172674	WormBaseID:	WBGene00003953	Length:	236	Species:	Caenorhabditis elegans

Alignment Length:	218	Identity:	70/218 - (32%)
Similarity:	126/218 - (57%)	Gaps:	11/218 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 TGTSVLGIRYDSGVMLAADTLVSYGSMARYQNIERVFKVNKNILLGGSGDFADIQSIKRNIDQKM 120
            |||||:.::|.:||::..|.:||||.||||:|:.|.:|||.|:|:...||.||...::..|::::
Worm    16 TGTSVIALQYKTGVVVLTDRVVSYGKMARYKNVSRQYKVNDNVLIAFGGDHADFHWLQNVIERQV 80

  Fly   121 IEDQCCDDNIEMKPKSLASWMTRVLYNRRSRMNPLYIDVVVGGVDNE-------GTPYLANVDLR 178
            :..:..|.:|  .||:|..::|.:||.:|.:|||::..:||.||:.|       .||::..:..:
Worm    81 LLWKRFDQDI--GPKALHGYLTSLLYAKRCKMNPVWNTLVVAGVEEEEKNNKETSTPFIGVITQK 143

  Fly   179 GRSYEDYVVATGFARHLAVPLVREK-KPKDRDFTAVEASELIRTCMEVLYYRDTRNISQYTVG-V 241
            |.:|:...:|||....|....|.:: :.|..|.:..||..::|..:|:..|.|....:::.:| |
Worm   144 GCAYQVKHIATGLGAFLLNQAVEDEWRKKGEDLSREEAEAVLRKSLELTLYHDCVADNEFEIGRV 208

  Fly   242 CSVNGCGVEGPFQVNENWTFAET 264
            .:..|..:....::..:|:.|||
Worm   209 DATEGVVLGKEEKIIGDWSIAET 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta7	NP_649529.1	proteasome_beta_type_4	60..252	CDD:239729	62/200 (31%)
Prosbeta7	NP_649529.1	PRE1	60..232	CDD:223711	59/179 (33%)
pbs-7	NP_492354.1	PRE1	16..221	CDD:223711	66/206 (32%)
pbs-7	NP_492354.1	proteasome_beta_type_4	16..218	CDD:239729	66/203 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164008
Domainoid	1	1.000	118	1.000	Domainoid score	I3681
eggNOG	1	0.900	-	-		E1_KOG0185
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	122	1.000	Inparanoid score	I3322
Isobase	1	0.950	-	0	Normalized mean entropy	S1013
OMA	1	1.010	-	-		QHG53720
OrthoDB	1	1.010	-	-		D1228942at2759
OrthoFinder	1	1.000	-	-		FOG0004376
OrthoInspector	1	1.000	-	-		oto17820
orthoMCL	1	0.900	-	-		OOG6_101718
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1012
SonicParanoid	1	1.000	-	-		X3101
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.750