DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11999 and PMT6

DIOPT Version :9

Sequence 1:	NP_649527.1	Gene:	CG11999 / 40637	FlyBaseID:	FBgn0037312	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_011715.1	Gene:	PMT6 / 853113	SGDID:	S000003431	Length:	759	Species:	Saccharomyces cerevisiae

Alignment Length:	199	Identity:	71/199 - (35%)
Similarity:	85/199 - (42%)	Gaps:	44/199 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LHSHDVKYGSGSGQQSVTGVEQKEDVNSHWVIK---------AQTGELCERGEPIACGSTVRLEH 99
            ||||...|..||||:.:||. ...|.|:.|..:         .|.|.|..:..||..|..|||.|
Yeast   361 LHSHIQVYPEGSGQRQITGY-GFADSNNVWKFEFSRSSGLELDQNGTLNGKIIPITDGVEVRLSH 424

  Fly   100 LSTKKNLHSHHFSSPLS-GEQEVSAYGTDGLGDTGDHWEV-----------VCSNEN----WMRS 148
            .:|..|||||...|.:| |..|||.||:..:||..|.|.|           |.||||    ...|
Yeast   425 KNTGSNLHSHDVPSHVSRGNYEVSGYGSQSVGDEKDDWIVEIVKQMDSPNPVYSNENSTILHPVS 489

  Fly   149 AHVRLRHIDTGMYLGMSGRSYGRPISG--QMEIV---GVHKPQHGTRWT----------TAEGLF 198
            ...||||...|.||..:|.:|  |..|  |.|||   ...:....|.|.          |||. :
Yeast   490 TFFRLRHKVLGCYLASTGLTY--PAWGFKQAEIVCKDSWSRRDKSTWWNVEDHWNHNLETAED-Y 551

  Fly   199 IVPK 202
            :.||
Yeast   552 VPPK 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11999	NP_649527.1	MIR	26..75	CDD:197746	14/30 (47%)
		MIR	86..138	CDD:197746	25/52 (48%)
		MIR	151..>182	CDD:197746	15/35 (43%)
PMT6	NP_011715.1	PMT1	44..759	CDD:224839	71/199 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1928
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2064
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2235
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.790