DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11999 and PMT5

DIOPT Version :9

Sequence 1:	NP_649527.1	Gene:	CG11999 / 40637	FlyBaseID:	FBgn0037312	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_010190.1	Gene:	PMT5 / 851464	SGDID:	S000002251	Length:	743	Species:	Saccharomyces cerevisiae

Alignment Length:	213	Identity:	60/213 - (28%)
Similarity:	84/213 - (39%)	Gaps:	53/213 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VGSISRGAATESN-VVTCGSILKLLNSDYAFRLHSHDVKYGSGSGQQSVTGVEQKEDVNSHWVIK 76
            |..::.|:|...| |.|.|..           ||||...|.:||.||.|| :....|.|:.|:|
Yeast   320 VAEVAVGSAVSLNHVGTAGGY-----------LHSHLHNYPAGSMQQQVT-LYPHIDQNNKWII- 371

  Fly    77 AQTGELCERG-------EPIACGSTVRLEHLSTKKNLHSHHFSSPLS----GEQEVSAYGTDGL- 129
                ||.|..       :.:..|:.::|..|.....||||....|:|    .::|||.||.:|.
Yeast   372 ----ELAEHPNENVTSFQNLTDGTIIKLRQLKNGCRLHSHDHKPPVSQNADWQKEVSCYGYEGFE 432

  Fly   130 GDTGDHWEVVCS---NENWMRSAHV-------RLRHIDTGMYLGMSGRSYGRPIS------GQME 178
            ||..|.|.:...   :|......|:       ||:|..||.||      :..|..      ||.|
Yeast   433 GDINDDWIIEIDKKRSEPGPAQEHIRAIETKFRLKHYLTGCYL------FSHPEKLPEWGFGQQE 491

  Fly   179 IVGVHKPQHG-TRWTTAE 195
            :...:..:.. |.|...|
Yeast   492 VTCAYFAREDLTSWYIEE 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11999	NP_649527.1	MIR	26..75	CDD:197746	17/48 (35%)
		MIR	86..138	CDD:197746	19/63 (30%)
		MIR	151..>182	CDD:197746	11/43 (26%)
PMT5	NP_010190.1	PMT1	22..729	CDD:224839	60/213 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343445
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1928
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2064
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2235
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720