DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11999 and POMT2

DIOPT Version :9

Sequence 1:	NP_649527.1	Gene:	CG11999 / 40637	FlyBaseID:	FBgn0037312	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	XP_011534977.1	Gene:	POMT2 / 29954	HGNCID:	19743	Length:	813	Species:	Homo sapiens

Alignment Length:	157	Identity:	53/157 - (33%)
Similarity:	78/157 - (49%)	Gaps:	25/157 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GSILKLLNSDYAF-RLHSHDVKY--GSGSGQQSVTGVEQKEDVNSHWVIKAQTGELCERGEP--- 88
            ||::.:.|...|. .||||...|  |.|:.||.||....| |.|:.|:||...    ...:|
Human   340 GSVITVKNLRMAIGYLHSHRHLYPEGIGARQQQVTTYLHK-DYNNLWIIKKHN----TNSDPLDP 399

  Fly    89 ------IACGSTVRLEHLSTKKNLHSHHFSSPLSGEQ-EVSAYGTDGLGDTGDHWEVVCSNENW- 145
                  :..|..:||||..|.:|||||:..:|::.:. :|:.||.:|.||:.|.|.:...|..:
Human   400 SFPVEFVRHGDIIRLEHKETSRNLHSHYHEAPMTRKHYQVTGYGINGTGDSNDFWRIEVVNRKFG 464

  Fly   146 -----MRSAHVRLRHIDTGMYLGMSGR 167
                 :|| .:|..|:.||..||.||:
Human   465 NRIKVLRS-RIRFIHLVTGCVLGSSGK 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11999	NP_649527.1	MIR	26..75	CDD:197746	19/47 (40%)
		MIR	86..138	CDD:197746	21/61 (34%)
		MIR	151..>182	CDD:197746	8/17 (47%)
POMT2	XP_011534977.1	PMT1	50..813	CDD:224839	53/157 (34%)
		PMT	62..306	CDD:280519
		MIR	334..390	CDD:197746	21/50 (42%)
		MIR	404..459	CDD:197746	20/54 (37%)
		MIR	472..521	CDD:197746	9/20 (45%)
		PMT_4TMC	538..811	CDD:292810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1928
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2235
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840