Protein Alignment CG11999 and SDF2L1

DIOPT Version :10

• Sequence 1: NP_649527.1
• Gene: CG11999 / 40637
• FlyBaseID: FBgn0037312
• Length: 216
• Species: Drosophila melanogaster
• Sequence 2: NP_071327.2
• Gene: SDF2L1 / 23753
• HGNCID: 10676
• Length: 221
• Species: Homo sapiens
• Alignment Length: 208
• Identity: 108/208 - (51%)
• Similarity: 136/208 - (65%)
• Gaps: 3/208 - (1%)

  Fly     6 LLTGLALVGSISRGAA--TESNVVTCGSILKLLNSDYAFRLHSHDVKYGSGSGQQSVTGVEQKED 68
            :|.||.|...:..|.|  |.:.:|||||:|||||:.:..||||||:|||||||||||||||..:|
Human    13 VLLGLLLALLVPGGGAAKTGAELVTCGSVLKLLNTHHRVRLHSHDIKYGSGSGQQSVTGVEASDD 77

  Fly    69 VNSHWVIKAQTGELCERGEPIACGSTVRLEHLSTKKNLHSHHFSSPLSGEQEVSAYGTDGLGDTG 133
            .||:|.|:..:...|.||.|:.||..|||.|:.|.||||:|||.||||..|||||:|.||.||..
Human    78 ANSYWRIRGGSEGGCPRGSPVRCGQAVRLTHVLTGKNLHTHHFPSPLSNNQEVSAFGEDGEGDDL 142

  Fly   134 DHWEVVCSNENWMRSAHVRLRHIDTGMYLGMSGRSYGRPISGQMEIVGVHKPQHGTRWTTAEGLF 198
            |.|.|.||.::|.|.|.||.:|:.|.::|.::|..||.||.||.|:.|:........|...||:|
Human   143 DLWTVRCSGQHWEREAAVRFQHVGTSVFLSVTGEQYGSPIRGQHEVHGMPSANTHNTWKAMEGIF 207

  Fly   199 IVPK-EKSSTHDE 210
            |.|. |.|:.|||
Human   208 IKPSVEPSAGHDE 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11999	NP_649527.1	beta-trefoil_MIR_SDF2_meta	27..201	CDD:467764	95/173 (55%)
SDF2L1	NP_071327.2	beta-trefoil_MIR_SDF2_meta	36..210	CDD:467764	95/173 (55%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	218..221		3/3 (100%)