DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11999 and R12E2.13

DIOPT Version :9

Sequence 1:	NP_649527.1	Gene:	CG11999 / 40637	FlyBaseID:	FBgn0037312	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_491320.1	Gene:	R12E2.13 / 172010	WormBaseID:	WBGene00020038	Length:	206	Species:	Caenorhabditis elegans

Alignment Length:	186	Identity:	94/186 - (50%)
Similarity:	127/186 - (68%)	Gaps:	1/186 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 AATESNVVTCGSILKLLNSDYAFRLHSHDVKYGSGSGQQSVTGVEQKEDVNSHWVIKAQTGELCE 84
            |..:.:.|||.|:||.:|::...|||||||||||||||||||.|:..:|:||||.|.......|.
Worm    19 AYADEDFVTCYSVLKFINANDGSRLHSHDVKYGSGSGQQSVTAVKNSDDINSHWQIFPALNAKCN 83

  Fly    85 RGEPIACGSTVRLEHLSTKKNLHSHHFSSPLSGE-QEVSAYGTDGLGDTGDHWEVVCSNENWMRS 148
            ||:.|.||..:||:||:|...||||||::|||.: |||||:|::...||||.|.|:|:.:.|:.|
Worm    84 RGDAIKCGDKIRLKHLTTGTFLHSHHFTAPLSKQHQEVSAFGSEAESDTGDDWTVICNGDEWLES 148

  Fly   149 AHVRLRHIDTGMYLGMSGRSYGRPISGQMEIVGVHKPQHGTRWTTAEGLFIVPKEK 204
            ...:|||..||.||.:||:.:||||.||.|:||......|:.|..|||::|..::|
Worm   149 EQFKLRHAVTGSYLSLSGQQFGRPIHGQREVVGTDSITGGSAWKVAEGIYIKHQQK 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11999	NP_649527.1	MIR	26..75	CDD:197746	32/48 (67%)
		MIR	86..138	CDD:197746	29/52 (56%)
		MIR	151..>182	CDD:197746	17/30 (57%)
R12E2.13	NP_491320.1	MIR	23..77	CDD:197746	33/53 (62%)
		MIR	34..180	CDD:280906	78/145 (54%)
		MIR	85..141	CDD:197746	30/55 (55%)
		MIR	143..195	CDD:197746	22/51 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	118	1.000	Domainoid score	I3667
eggNOG	1	0.900	-	-		E1_COG1928
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5045
Inparanoid	1	1.050	205	1.000	Inparanoid score	I2434
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54450
OrthoDB	1	1.010	-	-		D1534407at2759
OrthoFinder	1	1.000	-	-		FOG0002719
OrthoInspector	1	1.000	-	-		oto18888
orthoMCL	1	0.900	-	-		OOG6_102590
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2235
SonicParanoid	1	1.000	-	-		X2096
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810