DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hph and egln3

DIOPT Version :9

Sequence 1:	NP_001287171.1	Gene:	Hph / 40633	FlyBaseID:	FBgn0264785	Length:	478	Species:	Drosophila melanogaster
Sequence 2:	XP_005169871.1	Gene:	egln3 / 406602	ZFINID:	ZDB-GENE-040426-2541	Length:	271	Species:	Danio rerio

Alignment Length:	212	Identity:	114/212 - (53%)
Similarity:	144/212 - (67%)	Gaps:	10/212 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 IISDMNQYGLSVVDDFLGMETGLKILNEVRSMYNAGAFQDGQVVTNQTPDAPAVRGDKIRGDKIK 261
            ::..||.|||.::|.|||...|.::|.|||.::.:|..||||:.:.:...:.|     ||||||.
Zfish    55 VVPCMNSYGLCIIDRFLGDRIGERVLQEVRRIHQSGGMQDGQLASQKLDKSKA-----IRGDKIA 114

  Fly   262 WVGGNEPGCSNVWYLTNQIDSVVYRVNTMKDNGILGNYHIRERTRAMVACYPGSGTHYVMHVDNP 326
            ||||.|..|.|:.||..::|.::    |..| |.|..:.|..|.:||||||||:|..||.|||||
Zfish   115 WVGGTEGSCQNIGYLLTRMDKLI----TCAD-GRLDKFKITGRHKAMVACYPGNGAGYVKHVDNP 174

  Fly   327 QKDGRVITAIYYLNINWDARESGGILRIRPTPGTTVADIEPKFDRLIFFWSDIRNPHEVQPAHRT 391
            ..|||.:|.|||||.||:|:|.||:|||.|.....||||||.||||:.||||.||||||||::.|
Zfish   175 NADGRCVTCIYYLNKNWNAKEHGGLLRIFPEGKPYVADIEPLFDRLLLFWSDRRNPHEVQPSYAT 239

  Fly   392 RYAITVWYFDAKEREEA 408
            ||||||||||::||.||
Zfish   240 RYAITVWYFDSEERAEA 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hph	NP_001287171.1	zf-MYND	30..67	CDD:280009
Hph	NP_001287171.1	P4Hc	220..400	CDD:214780	97/179 (54%)
egln3	XP_005169871.1	P4Hc	72..248	CDD:214780	99/185 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	150	1.000	Domainoid score	I4348
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1604981at2759
OrthoFinder	1	1.000	-	-		FOG0001437
OrthoInspector	1	1.000	-	-		otm24982
orthoMCL	1	0.900	-	-		OOG6_104186
Panther	1	1.100	-	-	O	PTHR12907
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3122
SonicParanoid	1	1.000	-	-		X899
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.950