Protein Alignment Hph and Egln1

DIOPT Version :10

• Sequence 1: NP_730906.1
• Gene: Hph / 40633
• FlyBaseID: FBgn0264785
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: NP_848017.2
• Gene: Egln1 / 308913
• RGDID: 631375
• Length: 401
• Species: Rattus norvegicus
• Alignment Length: 430
• Identity: 173/430 - (40%)
• Similarity: 218/430 - (50%)
• Gaps: 81/430 - (18%)

  Fly    12 ASHSGSHSA-SKSAMDPPRCSICGTQQQLLRCAKCKAVYYCSPAHQHLHWPDHRTECRLLTRQKL 75
            ||.||.... |.|..|...|.:||..:.||||.:|::.:||...||...|..|:..|:
  Rat     2 ASDSGGPGVLSASERDRQYCELCGKMENLLRCGRCRSSFYCCKEHQRQDWKKHKLVCQ------- 59

  Fly    76 NSSNNNKQQQRQQIQQLQQAVASANLECSGA----GA----NCSTAQMMTP----AHQAQSWPAE 128
                 ..:..|.|....|..||.......||    ||    :.|||....|    |.||.|.|..
  Rat    60 -----GGEAPRAQPAPAQPRVAPPPGGAPGAARAGGAARRGDSSTAASRVPGPEDATQAGSGPGP 119

  Fly   129 VD-----------------NLLNLLGQPGSQEKAAAAETETGQRQQQHQHHHHNGEKSSSYQIGL 176
            .:                 :|....|.||.     |.....|.|.        ||:......:.|
  Rat   120 AEPSSEDPPPSRSPGPERASLCPAGGGPGE-----ALSPSGGLRP--------NGQTKPLPALKL 171

  Fly   177 ADASFMGSGSERRYEDLCRNIISDMNQYGLSVVDDFLGMETGLKILNEVRSMYNAGAFQDGQVVT 241
            |                ...|:..||::|:.|||||||.|||.:|.:|||::::.|.|.|||:|:
  Rat   172 A----------------LEYIVPCMNKHGICVVDDFLGRETGQQIGDEVRALHDTGKFTDGQLVS 220

  Fly   242 NQTPDAPAVRGDKIRGDKIKWVGGNEPGCSNVWYLTNQIDSVVYRVNTMKDNGILGNYHIRERTR 306
            .::..:     ..||||||.|:.|.||||..:..|.:.:|.::...     :|.||||.|..||:
  Rat   221 QKSDSS-----KDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHC-----SGKLGNYRINGRTK 275

  Fly   307 AMVACYPGSGTHYVMHVDNPQKDGRVITAIYYLNINWDARESGGILRIRPTPGTTVADIEPKFDR 371
            ||||||||:||.||.|||||..|||.:|.|||||.:|||:.|||||||.|......|||||||||
  Rat   276 AMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDR 340

  Fly   372 LIFFWSDIRNPHEVQPAHRTRYAITVWYFDAKEREEALIR 411
            |:|||||.|||||||||:.||||||||||||.||..|.::
  Rat   341 LLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVK 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hph	NP_730906.1	zf-MYND	30..67	CDD:460312	14/36 (39%)
		P4Hc	220..400	CDD:214780	101/179 (56%)
Egln1	NP_848017.2	zf-MYND	21..58	CDD:460312	14/36 (39%)
		PHA03247	<63..168	CDD:223021	27/117 (23%)
		P4Hc	193..369	CDD:214780	105/185 (57%)