Protein Alignment Hph and Hph

DIOPT Version :10

• Sequence 1: NP_730906.1
• Gene: Hph / 40633
• FlyBaseID: FBgn0264785
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: XP_313264.6
• Gene: Hph / 1274180
• VectorBaseID: AGAMI1_013969
• Length: 741
• Species: Anopheles gambiae
• Alignment Length: 684
• Identity: 199/684 - (29%)
• Similarity: 269/684 - (39%)
• Gaps: 300/684 - (43%)

  Fly    29 RCSICGTQQQLLRCAKCKAVYYCSPAHQHLHWPDHRTECRLL----------------------- 70
            :|.|||..:.|.||::|:..||||..||.:.|..|:.|||.:
Mosquito    63 QCRICGVSEGLRRCSRCQIAYYCSVDHQRVDWKVHKLECRSIHQPQQPFGIVCPSAGQQQPTPGQ 127

  Fly    71 ----------------------TRQKL---NSSNNN-----------------KQQQRQQIQQLQ 93
                                  .|.::   |.|.|.                 .|....|.|..|
Mosquito   128 PGNVVMPTAGTATVPMSEGSFCVRAEMLGPNGSTNTTTIGGGFVPQAPNVNIASQPSLPQSQAGQ 192

  Fly    94 QAVASANLECS-----------------------GAG------------ANCSTAQMMTPAHQ-- 121
            ..|.:|....:                       |.|            |.|:..|..|.|..
Mosquito   193 NVVTAAAAAATVIAPSATTPPAQTIASTVVGPAFGGGRGLLLPAAATSAATCARTQQSTIASDGS 257

  Fly   122 ------------AQSWP---------------AEVDNLLN------------------------- 134
                        ::.:|               .:||::||
Mosquito   258 DSGDEFLNELAVSKLFPIDALASAEELADLDQLDVDHILNENNFLNNINNLNVFDGTEQQPEPLI 322

  Fly   135 ----------------------------------------------------------------- 134
                                                                             
Mosquito   323 QPEFAATDSVNQNFSGGGDAFLNNNNNFVNSSVLLVGTGGGGQGHEQLGNRYGEETAATMQLAQS 387

  Fly   135 ----LLGQPG----------SQEKAAAAETETGQRQQQHQ----HHHHNGEKSSSYQIGLAD--- 178
                ||.||.          .|::.|.|:.:  |:|||.|    ....:|....|..:...|
Mosquito   388 GSVMLLQQPQHPPQQKQNHLEQQRTAKAQQQ--QQQQQQQLAALFRQASGAVDGSPVLAKVDVTN 450

  Fly   179 -----ASFMGSGSERR-------------------------------------------YEDLCR 195
                 |..:|...:.|                                           .::.||
Mosquito   451 SDAASALLLGGKQDNRKGRTVQANGAPGANVTLGIPTGVSGPVSAGVLEPCPFDFDSDSLDEACR 515

  Fly   196 NIISDMNQYGLSVVDDFLGMETGLKILNEVRSMYNAGAFQDGQVVTNQTPDAPAVRGDKIRGDKI 260
            ::|.|||:||:.|:|:|||.|.|.::|:||..||::|.|:|||:|:|:  .|..:|  .||||||
Mosquito   516 SLIRDMNEYGVCVLDNFLGQERGQQVLDEVTGMYSSGVFRDGQLVSNR--GANNLR--HIRGDKI 576

  Fly   261 KWVGGNEPGCSNVWYLTNQIDSVVYRVNTMKDNGILGNYHIRERTRAMVACYPGSGTHYVMHVDN 325
            .|:||.|||||::.||.|.:|:|:.....|::||.||.|:|:|||:||||||||||:|||.||||
Mosquito   577 TWIGGKEPGCSSIGYLINCVDAVITNCKRMENNGKLGRYNIKERTKAMVACYPGSGSHYVKHVDN 641

  Fly   326 PQKDGRVITAIYYLNINWDARESGGILRIRPTP-GTTVADIEPKFDRLIFFWSDIRNPHEVQPAH 389
            |.:|||.||||||||::||.|:|||:|||.|.. ...||||||.|||::|||||.||||||||||
Mosquito   642 PNRDGRCITAIYYLNLDWDVRKSGGLLRIFPEGCNDRVADIEPIFDRILFFWSDRRNPHEVQPAH 706

  Fly   390 RTRYAITVWYFDAKEREEALIRAKLE-----NSK 418
            |||||||:||.||:|||.|.:|.:.:     |||
Mosquito   707 RTRYAITLWYLDAEERESARLRYQRDCENRFNSK 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hph	NP_730906.1	zf-MYND	30..67	CDD:460312	16/36 (44%)
		P4Hc	220..400	CDD:214780	114/180 (63%)
Hph	XP_313264.6	None