Protein Alignment Hph and Egln3

DIOPT Version :9

• Sequence 1: NP_001287171.1
• Gene: Hph / 40633
• FlyBaseID: FBgn0264785
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: NP_082409.2
• Gene: Egln3 / 112407
• MGIID: 1932288
• Length: 239
• Species: Mus musculus
• Alignment Length: 238
• Identity: 114/238 - (47%)
• Similarity: 153/238 - (64%)
• Gaps: 20/238 - (8%)

  Fly   197 IISDMNQYGLSVVDDFLGMETGLKILNEVRSMYNAGAFQDGQVVTNQTPDAPAVRGDK--IRGDK 259
            |:..:::.|...:|:|||...|..:|..|:.::..||.:|||:.      .|.....|  :|||:
Mouse    19 IVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHYNGALRDGQLA------GPCAGVSKRHLRGDQ 77

  Fly   260 IKWVGGNEPGCSNVWYLTNQIDSVVYRVNTMKDNGILGNYHIRERTRAMVACYPGSGTHYVMHVD 324
            |.|:||||.||..:.:|.:.||.:|....:.     ||.|:::||::||||||||:||.||.|||
Mouse    78 ITWIGGNEEGCEAINFLLSLIDRLVLYCGSR-----LGKYYVKERSKAMVACYPGNGTGYVRHVD 137

  Fly   325 NPQKDGRVITAIYYLNINWDARESGGILRIRPTPGTTVADIEPKFDRLIFFWSDIRNPHEVQPAH 389
            ||..|||.||.|||||.||||:..||:|||.|...:.|||:||.||||:|||||.||||||||::
Mouse   138 NPNGDGRCITCIYYLNKNWDAKLHGGVLRIFPEGKSFVADVEPIFDRLLFFWSDRRNPHEVQPSY 202

  Fly   390 RTRYAITVWYFDAKEREEALIRAKLENSKTNNLAAQAQAQQAE 432
            .||||:|||||||:||.||       ..|..||..:.::..|:
Mouse   203 ATRYAMTVWYFDAEERAEA-------KKKFRNLTRKTESALAK 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hph	NP_001287171.1	zf-MYND	30..67	CDD:280009
		P4Hc	220..400	CDD:214780	95/181 (52%)
Egln3	NP_082409.2	P4Hc	36..213	CDD:214780	97/187 (52%)
		Beta(2)beta(3) 'finger-like' loop. /evidence=ECO:0000250|UniProtKB:Q9GZT9	62..73		2/16 (13%)
		Required for interaction with ADRB2. /evidence=ECO:0000250|UniProtKB:Q9H6Z9	88..104		5/15 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	151	1.000	Domainoid score	I4334
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2936
Isobase	1	0.950	-	0	Normalized mean entropy	S4690
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1604981at2759
OrthoFinder	1	1.000	-	-		FOG0001437
OrthoInspector	1	1.000	-	-		otm43662
orthoMCL	1	0.900	-	-		OOG6_104186
Panther	1	1.100	-	-	O	PTHR12907
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3122
SonicParanoid	1	1.000	-	-		X899
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.950