DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hph and egln3

DIOPT Version :9

Sequence 1:	NP_001287171.1	Gene:	Hph / 40633	FlyBaseID:	FBgn0264785	Length:	478	Species:	Drosophila melanogaster
Sequence 2:	NP_001120484.1	Gene:	egln3 / 100145602	XenbaseID:	XB-GENE-964334	Length:	252	Species:	Xenopus tropicalis

Alignment Length:	236	Identity:	118/236 - (50%)
Similarity:	146/236 - (61%)	Gaps:	26/236 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 GLSVVDDFLGMETGLKILNEVRSMYNAGAFQDGQVVTNQTPDAPAVRGDKIRGDKIKWVGGNEPG 269
            |...:|:|||.|.|.::|.:||.:|..||.:|||:..:    ...|....:|||||.||.|.|.|
Frog    39 GYCYLDNFLGEEIGNRVLEKVRRLYQDGALKDGQLAGH----LQGVSKKHLRGDKIAWVAGTEEG 99

  Fly   270 CSNVWYLTNQIDSVVYRVNTMKDNGILGNYHIRERTRAMVACYPGSGTHYVMHVDNPQKDGRVIT 334
            |..:..:.:.||.:|     |.....||.|:::||::||||||||:|..||.|||||..|||.||
Frog   100 CEAIGLVLSVIDRLV-----MLCGNRLGQYYVKERSKAMVACYPGNGAGYVRHVDNPTGDGRCIT 159

  Fly   335 AIYYLNINWDARESGGILRIRPTPGTTVADIEPKFDRLIFFWSDIRNPHEVQPAHRTRYAITVWY 399
            .|||||.:|||:..||||||.|..|..||||||.||||:|||||.||||||||::.||||:||||
Frog   160 CIYYLNKDWDAKIHGGILRIFPEGGPHVADIEPLFDRLLFFWSDRRNPHEVQPSYSTRYALTVWY 224

  Fly   400 FDAKEREEALIRAKLENSKTNNLAAQAQAQQAEPDSTTTPP 440
            ||||||                 ||..|..:...:||..||
Frog   225 FDAKER-----------------AAAKQKFKRLSESTEEPP 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hph	NP_001287171.1	zf-MYND	30..67	CDD:280009
Hph	NP_001287171.1	P4Hc	220..400	CDD:214780	97/179 (54%)
egln3	NP_001120484.1	P4Hc	54..225	CDD:214780	97/179 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	146	1.000	Domainoid score	I4505
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1604981at2759
OrthoFinder	1	1.000	-	-		FOG0001437
OrthoInspector	1	1.000	-	-		otm48835
Panther	1	1.100	-	-	O	PTHR12907
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X899
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.020