DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tim17a2 and TIMM17A

DIOPT Version :9

Sequence 1:	NP_649524.1	Gene:	Tim17a2 / 40632	FlyBaseID:	FBgn0037307	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_006326.1	Gene:	TIMM17A / 10440	HGNCID:	17315	Length:	171	Species:	Homo sapiens

Alignment Length:	137	Identity:	76/137 - (55%)
Similarity:	99/137 - (72%)	Gaps:	1/137 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EYNRQPCPIRIVEDCGCAFMMGTMGGSLFQYLKGFRNAPSGLRRGLHGGIESVRLRTPAIAGSFA 66
            ||.|:|||.|||:|||.||.|||:||.:||.:|||||:|.|:...|.|.:.:::.|.|.:.||||
Human     3 EYAREPCPWRIVDDCGGAFTMGTIGGGIFQAIKGFRNSPVGVNHRLRGSLTAIKTRAPQLGGSFA 67

  Fly    67 IWGATFSTVDCVMVSYRQREDSWNAIVSGAATGGILAARNGIRAMANSAFVGCLVLAMLEGAGAA 131
            :||..||.:||.||..|.:||.||:|.|||.||.|||||||..||..||.:|.::||::|||| .
Human    68 VWGGLFSMIDCSMVQVRGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGGILLALIEGAG-I 131

  Fly   132 VATIYAS 138
            :.|.:||
Human   132 LLTRFAS 138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tim17a2	NP_649524.1	Tim17	2..>129	CDD:295283	71/126 (56%)
TIMM17A	NP_006326.1	3a0801so1tim17	1..171	CDD:130053	76/137 (55%)
TIMM17A	NP_006326.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	144..171
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152386
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5596
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1590221at2759
OrthoFinder	1	1.000	-	-		FOG0001103
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10485
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X753
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.810